Results 51 to 60 of about 451,671 (152)

CMSA: a heterogeneous CPU/GPU computing system for multiple similar RNA/DNA sequence alignment

open access: yesBMC Bioinformatics, 2017
Background The multiple sequence alignment (MSA) is a classic and powerful technique for sequence analysis in bioinformatics. With the rapid growth of biological datasets, MSA parallelization becomes necessary to keep its running time in an acceptable ...
Xi Chen   +4 more
doaj   +1 more source

Vertical decomposition with Genetic Algorithm for Multiple Sequence Alignment

open access: yesBMC Bioinformatics, 2011
Background Many Bioinformatics studies begin with a multiple sequence alignment as the foundation for their research. This is because multiple sequence alignment can be a useful technique for studying molecular evolution and analyzing sequence structure ...
Essam Daryl   +2 more
doaj   +1 more source

A multiple sequence alignment program

open access: yesNucleic Acids Research, 1986
A program is described for simultaneously aligning two or more molecular sequences which is based on first finding common segments above a specified length and then piecing these together to maximize an alignment scoring function. Optimal as well as near-optimal alignments are found, and there is also provided a means for randomizing the given ...
E, Sobel, H M, Martinez
openaire   +3 more sources

Automatic detection of anchor points for multiple sequence alignment

open access: yesBMC Bioinformatics, 2010
Background Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software.
Pitschi Florian   +2 more
doaj   +1 more source

Multiple sequence alignment by consensus [PDF]

open access: yesNucleic Acids Research, 1986
An algorithm for multiple sequence alignment is given that matches words of length and degree of mismatch chosen by the user. The alignment maximizes an alignment scoring function. The method is based on a novel extension of our consensus sequence methods.
openaire   +2 more sources

Kalign – an accurate and fast multiple sequence alignment algorithm

open access: yesBMC Bioinformatics, 2005
Background The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families for conserved motifs, phylogeny, structural properties, and to improve ...
Sonnhammer Erik LL, Lassmann Timo
doaj   +1 more source

A comprehensive systematic literature review of multiple sequence alignment algorithms

open access: yesDiscover Computing
Multiple sequence alignment (MSA) is a fundamental technique in computational biology that compares protein, DNA, or RNA sequences to identify regions of similarity reflecting functional, structural, or evolutionary relationships.
Jeneffer Sabonsolin, Demelo Lao
doaj   +1 more source

DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment

open access: yesBMC Bioinformatics, 2005
Background We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous version 2.2 of DIALIGN.
Kaufmann Michael   +3 more
doaj   +1 more source

Multiple sequence alignment based on deep reinforcement learning with self-attention and positional encoding. [PDF]

open access: yesBioinformatics, 2023
Liu Y   +6 more
europepmc   +1 more source

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