Results 91 to 100 of about 896,852 (317)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Existence of nontrivial solutions for singular quasilinear equations with sign changing nonlinearity

Electronic Journal of Differential Equations, 2010
By an application of Bonanno's three critical point theorem, we establish the existence of a nontrivial solution to the problem $$displaylines{ -Delta_p u= mu frac{g(x)|u|^{p-2}u}{|x|^p} +lambda a(x)f(u) quad hbox{in }Omega,cr u =0quad hbox{on ...
Jagmohan Tyagi
doaj  

Multiple positive solutions for a class of concave-convex Schrödinger-Poisson-Slater equations with critical exponent

Advances in Nonlinear Analysis
In this article, we consider the multiplicity of positive solutions for a static Schrödinger-Poisson-Slater equation of the type −Δu+u2∗1∣4πx∣u=μf(x)∣u∣p−2u+g(x)∣u∣4uinR3,-\Delta u+\left({u}^{2}\ast \frac{1}{| 4\pi x| }\right)u=\mu f\left(x){| u| }^{p-2 ...
Zheng Tian-Tian, Lei Chun-Yu, Liao Jia-Feng   +2 more
doaj   +1 more source

Multiple solutions to a nonlocal sub-Laplacian system with critical growth and logarithmic perturbation

AIMS Mathematics
In this paper, we studied the existence of solutions for a nonlocal sub-Laplacian system with critical growth and logarithmic perturbation. That is to say, by using the symmetric mountain pass lemma, we proved that under some suitable conditions, the ...
Yu-Cheng An, Bi-Jun An
doaj   +1 more source

Multiple nontrivial solutions for $p$-Laplacian equations with an asymmetric nonlinearity [PDF]

, 2006
Shouchuan Hu, Nikolaos S. Papageorgiou
openalex   +1 more source

Bifurcation from interval and multiple positive solutions for a nonlinear fractional differential equations with integral boundary conditions

, 2023
Madjid Halaoua, El Amir Djeffal
openalex   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Multiple solutions in data fitting: a trap in EXAFS structural analysis and some ideas to avoid it [PDF]

, 1998
Alain Michalowicz, G. Vlaic
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Multiple solutions for a class of degenerate nonlocal problems involving sublinear nonlinearities

Le Matematiche, 2014
In this article, we use the three critical points theorem by G. Bonanno [3] in order to investigate the multiplicity of solutions for some nonlocal degenerate problems.
Nguyen Thanh Chung, Hoang Quoc Toan
doaj