Results 241 to 250 of about 795,757 (316)

Evaluating the utility of texting in the ambulatory care of paediatric patients with type 1 diabetes: a quality improvement report. [PDF]

BMJ Open Qual
Waida E, Wilkinson S, Brauer M.
europepmc   +1 more source

Kepler-445, Kepler-446 and the occurrence of compact multiples orbiting mid-M dwarf stars

, 2015
Philip S. Muirhead, Andrew W. Mann, Andrew Vanderburg, T.D. Morton, Adam L. Kraus, Michael Ireland, J.J. Swift, Gregory A. Feiden, Eric Gaidos, J. Zachary Gazak   +9 more
openalex   +2 more sources

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Revealing excitation-inhibition imbalance in Alzheimer's disease using multiscale neural model inversion of resting-state functional MRI. [PDF]

Commun Med (Lond)
Li G, Hsu LM, Wu Y, Bozoki AC, Shih YI, Yap PT.   +5 more
europepmc   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Stars by the Pocketful. [PDF]

ACS Cent Sci
Lavis CE, Lavis LD.
europepmc   +1 more source

Application of Multiple-imputation-particle-filter for Parameter Estimation of Visual Binary Stars with Incomplete Observations

, 2016
Rubén M. Clavería, David E. Acuña-Ureta, R. A. Méndez, Jorge F. Silva, Marcos E. Orchard   +4 more
openalex   +2 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Predicting the diversity of photosynthetic light-harvesting using thermodynamics and machine learning. [PDF]

PLoS Comput Biol
Gray C, Chitnavis S, Buja T, Duffy CDP.
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source