Results 51 to 60 of about 926 (212)

Multiplexity-facilitated cascades in networks [PDF]

Physical Review E, 2012
Elements of networks interact in many ways, so modeling them with graphs requires multiple types of edges (or network layers). Here we show that such multiplex networks are generically more vulnerable to global cascades than simplex networks. We generalize the threshold cascade model [D. J. Watts, Proc. Natl. Acad. Sci. U.S.A.
Brummitt, Charles D., Lee, Kyu-Min, Goh, K. -I.   +2 more
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Coupled Simultaneous Evolution of Policy, Enterprise Innovation Awareness, and Technology Diffusion in Multiplex Networks

Mathematics
This study comprehensively examines the coupling effect of government policies, enterprise behavior, and existing technology on the diffusion of innovative technology. Utilizing multiplex network theory, a multiplex network model is constructed to couple
Jingyi Wang, Rui Hu, Hua Xu
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

A Link Prediction Algorithm Based on Layer Attention Mechanism for Multiplex Networks

Mathematics
Link prediction is a technique for predicting future or missing relationships between entities based on current network information. Recent studies on link prediction in multiplex networks have improved prediction accuracy by considering inter-layer ...
Mingzhou Yang, Yongqi He
doaj   +1 more source

Synchronization Induced by Layer Mismatch in Multiplex Networks

Entropy, 2023
Heterogeneity among interacting units plays an important role in numerous biological and man-made complex systems. While the impacts of heterogeneity on synchronization, in terms of structural mismatch of the layers in multiplex networks, has been ...
Md Sayeed Anwar, Sarbendu Rakshit, Jürgen Kurths, Dibakar Ghosh   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Communication in multiplex transportation networks

Numerical Algorithms
Abstract Complex networks are made up of vertices and edges. The edges, which may be directed or undirected, are equipped with positive weights. Modeling complex systems that consist of different types of objects leads to multilayer networks, in which vertices in distinct layers represent different kinds of ...
Noschese S., Reichel L.
openaire   +2 more sources

Multiplex core of the human brain using structural, functional and metabolic connectivity derived from hybrid PET-MR imaging

Frontiers in Neuroimaging, 2023
With the increasing success of mapping brain networks and availability of multiple MR- and PET-based connectivity measures, the need for novel methodologies to unravel the structure and function of the brain at multiple spatial and temporal scales is ...
Martijn Devrome, Koen Van Laere, Koen Van Laere, Michel Koole   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source