Results 71 to 80 of about 926 (212)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Information transport in multiplex networks [PDF]
Physica A: Statistical Mechanics and its Applications, 2016 7figures
Cunlai Pu +4 more
openaire +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
New Journal of PhysicsMultiplex networks provide a powerful data structure for capturing diverse relationships among nodes, and the challenge of community detection within these networks has recently attracted considerable attention.
Fengqin Tang +3 more
doaj +1 more source
Layer Information Similarity Concerned Network Embedding
Complexity, 2021 Great achievements have been made in network embedding based on single-layer networks. However, there are a variety of scenarios and systems that can be presented as multiplex networks, which can reveal more interesting patterns hidden in the data ...
Ruili Lu +4 more
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Synchronization in delayed multiplex networks [PDF]
EPL (Europhysics Letters), 2015 We study impact of multiplexing on the global phase synchronizability of different layers in the delayed coupled multiplex networks. We find that at strong couplings, the multiplexing induces the global synchronization in sparse networks. The introduction of global synchrony depends on the connection density of the layers being multiplexed, which ...
Singh, A. +3 more
openaire +3 more sources
The Multiplex Dependency Structure of Financial Markets
Complexity, 2017 We propose here a multiplex network approach to investigate simultaneously different types of dependency in complex datasets. In particular, we consider multiplex networks made of four layers corresponding, respectively, to linear, nonlinear, tail, and ...
Nicolò Musmeci +4 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source