Results 61 to 70 of about 926 (212)

Subgraph Matching on Multiplex Networks

open access: yesIEEE Transactions on Network Science and Engineering, 2021
An active area of research in computational science is the design of algorithms for solving the subgraph matching problem to find copies of a given template graph in a larger world graph. Prior works have largely addressed single-channel networks using a variety of approaches.
Jacob D. Moorman   +4 more
openaire   +3 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Scalable Multiplex Network Embedding [PDF]

open access: yesProceedings of the Twenty-Seventh International Joint Conference on Artificial Intelligence, 2018
Network embedding has been proven to be helpful for many real-world problems. In this paper, we present a scalable multiplex network embedding model to represent information of multi-type relations into a unified embedding space. To combine information of different types of relations while maintaining their distinctive properties, for each node, we ...
Hongming Zhang 0009   +3 more
openaire   +1 more source

Multiplex graph matching matched filters

open access: yesApplied Network Science, 2022
We consider the problem of detecting a noisy induced multiplex template network in a larger multiplex background network. Our approach, which extends the graph matching matched filter framework of Sussman et al. (IEEE Trans Pattern Anal Mach Intell 42(11)
Konstantinos Pantazis   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Optimal percolation on multiplex networks [PDF]

open access: yesNature Communications, 2017
AbstractOptimal percolation is the problem of finding the minimal set of nodes whose removal from a network fragments the system into non-extensive disconnected clusters. The solution to this problem is important for strategies of immunization in disease spreading, and influence maximization in opinion dynamics.
Saeed Osat, Ali Faqeeh, Filippo Radicchi
openaire   +4 more sources

Cluster-based topological features of nodes in a multiplex network—from a network of networks perspective

open access: yesNew Journal of Physics, 2019
In the gathered multiplex systems, nodes inherit a part of their original system’s topological features, as in the world economic system, national policies and resource distribution bring industry advantages and resource advantages to the domestic ...
Feng An   +6 more
doaj   +1 more source

Identifying communities from multiplex biological networks [PDF]

open access: yesPeerJ, 2015
Various biological networks can be constructed, each featuring gene/protein relationships of different meanings (e.g., protein interactions or gene co-expression).
Gilles Didier   +2 more
doaj   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dynamical origins of the community structure of an online multi-layer society

open access: yesNew Journal of Physics, 2016
Social structures emerge as a result of individuals managing a variety of different social relationships. Societies can be represented as highly structured dynamic multiplex networks.
Peter Klimek   +4 more
doaj   +1 more source

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