Results 141 to 150 of about 25,229 (229)

Ectopia cordis cervicalis esete Holstein fríz borjúban Esetismertetés [PDF]

, 2016
A szerzők esetleírásukban bemutatják egy, ectopia cordis cervicalis fejlődési rendellenességben szenvedő, majd két napos korban elhullott, 36 kg testtömegű, Holstein Fríz fajtájú bika borjú rendellenesen helyeződő szívének kamra és pitvar falainak, a ...
Bikádi, Péter, Hornyák, Ákos, Jakab, Csaba, Krebsz, Máté, Kutasi, Péter, Somogyi, Attila, Szabára, Ágnes, Szabó, János, Végh, Borbála   +8 more
core  

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Using ngTALEN to improve genome editing efficiency on targets containing 5‐methylcytosines [PDF]

Plant J
SUMMARY We recently discovered distinct methylation patterns between the mitochondrial genome and the nuclear‐encoded mitochondrial DNA sequences (NUMTs), with the mitochondrial genome being hypomethylated and NUMTs being hypermethylated. Given that genome editing using mitochondrial targeted transcription activator‐like effector nucleases (TALEN) is ...
Wang Z, Tamura Y, Hashimoto M, Nakazato I, Yamaguchi‐Nishimura A, Arimura S.   +5 more
europepmc   +2 more sources

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

SaliVIR COVID19 Rapid Multiplex qRT-PCR Kit v1

, 2020
Daniel Elias Martin-Herranz, Thomas Stubbs   +1 more
openaire   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Sejt- és molekuláris biológiai vizsgálatok ultraibolya fény okozta dermatosisokban és bőrtumorokban. Nanoszkopikus (dendrimer) reaktorok kutatása a kémiai aktinometriában a prevencióban. = Cell and molecular biological investigations in UV-light induced skin disorders and skin tumours. A study on nanoscopic (dendritic) reactors in the chemical actinometry for preventive purpose. [PDF]

, 2007
UV-DNS károsodás és reparáció vizsgálatának beállítása, optimalizálása comet assay-vel humán keratinocytákban, egészségesek és hyperlipidaemiás betegek lymphocytáiban (kollab.: Atorvastatin-hatás oxidatív DNS károsodásra).
Balogh, Lajos, Bazsa, György, Emri, Gabriella, Horkay, Irén, Király, Róbert, Nagy, István, Országh, István, Remenyik, Éva, Simics, Enikő   +8 more
core  

Characterization of Human Group 9 Innate Lymphoid Cells in Response to Allergen Immunotherapy in Patients With Allergic Rhinitis

Allergy, EarlyView.
We aimed to report the existence and profile of group 9 innate lymphoid cells (ILC9s). Overall, ILC9 proportions in AR patients show differences compared to healthy subjects and responder SCIT patients. IL‐9 expression decreases after siRNA inhibition of Bach2 suggesting Bach2 could display as a transcription factor of ILC9.
Ya‐Qi Peng, Te Zhang, Xiao‐Qing Liu, Ismail Ogulur, Qi Sun, Beate Ruckert, Bi‐Xin He, De‐Hua Chen, Hideaki Morita, Hui‐Jing Ye, Qing‐Ling Fu, Cezmi A. Akdis   +11 more
wiley   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Fenofibrate potentiates the therapeutic efficacy of EZH2 inhibitors on melanoma via TRIM21‐ and OTUD4‐mediated EZH2 ubiquitination

British Journal of Pharmacology, EarlyView.
Background and Purpose EZH2 (enhancer of zeste homologue 2) inhibitors are an emerging class of drugs that target epigenetic regulation. However, their efficacy in solid tumours has been limited, partly due to drug‐induced upregulation of fatty acid synthesis.
Rui Cheng, Yuanjun Tang, Xuedi Cao, Xiaotong Yu, Zhanya Huang, Yunyun Guo, Renjing Jin, Yan Wang, Yang Liu, Lixiang Xue, Yuqing Wang   +10 more
wiley   +1 more source