Results 51 to 60 of about 283 (168)

Tiliqua rugosa microsatellites: isolation via enrichment and characterisation of loci for multiplex PCR in T. rugosa and the endangered T. adelaidensis

, 2008
The original publication is available at www.springerlink.comWe used an enrichment technique to isolate 18 novel di and tri microsatellites for the socially monogamous lizard Tiliqua rugosa.
Gardner, Michael G, Rheinberger, L., Smith, Annabel L, Dudaniec, Rachael Y, Saint, Kathleen M, Gardner, Michael, Saint, K., Gardner, Michael George, Smith, Annabel, Saint, Kathleen M., Sanchez, Juan J., Gardner, Michael G., Sanchez, J., Dudaniec, R., Gardner, M., Smith, A., Sanchez, J.J., Sanchez, Juan J, Smith, Annabel L., Dudaniec, Rachael, Rheinberger, Leah, Dudaniec, Rachael Y.   +21 more
core   +1 more source

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

Modeling forward stutter: Toward increased objectivity in forensic DNA interpretation

, 2019
Forward stutter, or over stutter, one repeat unit length larger than the parent allele (N+1 stutter), is a relatively rare product of the PCR amplification of short tandem repeats used in forensic DNA analysis.
Jo-Anne Bright (6547208), John S. Buckleton (6563462), James M. Curran (6520439), Duncan Taylor (6547206), M.A.C.S.S. Fernando (8064466)   +4 more
core   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Development of microsatellite multiplexes for wild goats using primers designed from domestic Bovidae

, 2001
Times Cited: 21International audienceMany wild goat taxa (Capra spp.) are endangered and would benefit from the availability of molecular tools that are useful for population management and conservation.
Luikart, G., Luikart, Gordon, Taberlet, Pierre, Taberlet, P., Maudet, C., Maudet, Celia   +5 more
core  

Rapid detection of novelBRCA1 rearrangements in high-risk breast-ovarian cancer families using multiplex PCR of short fluorescent fragments

, 2002
International audienceRecent studies have revealed a significant proportion of BRCA1 exon deletions or duplications in breast-ovarian cancer families with high probability of BRCA1- or BRCA2-linked predisposition, in which mutations of these genes have ...
Gad, Sophie, Di Rocco, Zorika Christiana, Frebourg, Thierry, Casilli, Federica, Tournier, Isabelle, Stoppa-Lyonnet, Dominique, Tosi, Mario   +6 more
core   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Typing of Y chromosome SNPs with multiplex PCR methods

, 2005
Udgivelsesdato: 2005We describe a method for the simultaneous typing of Y-chromosome single nucleotide polymorphism (SNP) markers by means of multiplex polymerase chain reaction (PCR) strategies that allow the detection of 35 Y chromosome SNPs on 25 ...
Morling, Niels, Sanchez Sanchez, Juan Jose, Børsting, Claus   +2 more
core  

Additional file 1: of Widespread occurrence of asexual reproduction in higher termites of the Termes group (Termitidae: Termitinae)

, 2019
Figure S1. Photographs of a female ergatoid (worker-derived) neotenic in Palmitermes impostor. Table S1. Composition of the sampled nests of P. impostor, S. trispinosus and I. inquilinus. Table S2.
Robert Hanus (307338), Klára Dolejšová (3291231), Denis Fournier (182310), Yves Roisin (307340), Simon Hellemans (3243690), Jan Křivánek (6867857)   +5 more
core   +1 more source