Results 41 to 50 of about 25,148 (302)

Two-Dimensional Harmonic Retrieval in Correlative Noise Based on Genetic Algorithm

EURASIP Journal on Advances in Signal Processing, 2010
We propose a niche Genetic algorithm (GA) for the two-dimensional (2D) harmonic retrieval in the presence of correlative zero-mean, multiplicative, and additive noise.
Sun-Yong Wu, Gui-Sheng Liao, Zhi-Wei Yang   +2 more
doaj   +2 more sources

Superring of Polynomials over a Hyperring

Mathematics, 2019
A Krasner hyperring (for short, a hyperring) is a generalization of a ring such that the addition is multivalued and the multiplication is as usual single valued and satisfies the usual ring properties.
Reza Ameri, Mansour Eyvazi, Sarka Hoskova-Mayerova   +2 more
doaj   +1 more source

Capturing the zero: a new class of zero-augmented distributions and multiplicative error processes [PDF]

, 2010
We propose a novel approach to model serially dependent positive-valued variables which realize a non-trivial proportion of zero outcomes. This is a typical phenomenon in financial time series observed on high frequencies, such as cumulated trading ...
Hautsch, Nikolaus, Schienle, Melanie, Malec, Peter   +2 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Milne-Type Inequalities in the Context of Conformable Fractional Multiplicative Integrals

Journal of Function Spaces
This paper examines Milne inequalities in the setting of conformal fractional multiplicative integrals, which represent a modern extension of traditional fractional calculus.
İrem Çay, Hüseyin Budak, İrem Bağlan   +2 more
doaj   +1 more source

Genetic basis for clinical expression in multiple sclerosis [PDF]

Brain, 2002
Multiple sclerosis is a clinically heterogeneous demyelinating disease and an important cause of acquired neurological disability. An underlying complex genetic susceptibility plays an important role in multiple sclerosis aetiology; however, the role of genetic factors in determining clinical features of multiple sclerosis is unknown.
null The Multiple Sclerosis Genetics Group, L. F. Barcellos, J. R. Oksenberg, A. J. Green, P. Bucher, J. B. Rimmler, S. Schmidt, M. E. Garcia, R. R Lincoln, M. A. Pericak‐Vance, J. L. Haines, S. L. Hauser   +11 more
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Real Time Multiplicative Memory Amplification Mediated by Whole-Cell Scaling of Synaptic Response in Key Neurons. [PDF]

PLoS Computational Biology, 2017
Intense spiking response of a memory-pattern is believed to play a crucial role both in normal learning and pathology, where it can create biased behavior.
Iris Reuveni, Sourav Ghosh, Edi Barkai
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source