Results 131 to 140 of about 1,789 (148)

Distribution of pericentriolar material in multipolar spindles induced by colcemid treatment in chinese hamster ovary cells [PDF]

Journal of Cell Science, 1988
ABSTRACT Mitotic Chinese hamster ovary cells were obtained by treatment with microtubule drugs under various conditions, and the shape of spindles was analysed by phase-contrast microscopy of isolated spindles, and by indirect immunofluorescence staining of whole mitotic cells with anti-tubulin antibody.
Caterina Sellitto, Ryoko Kuriyama
openalex   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Induction of multipolar spindles by single X-irradiated sperm

Experientia, 1959
Une experience simple de dilution etablit que les clivages multipolaires des œufs de oursins resultent de l'insemination par des spermatozoides individuels qui ont ete soumis aux rayons X.
openaire   +3 more sources

Bisphenol A disrupts microtubules and induces multipolar spindles in dividing root tip cells of the gymnosperm Abies cephalonica

Chemosphere, 2016
The effects of bisphenol A (BPA), an endocrine chemical disruptor extensively used in the plastic and epoxy resin industry, on dividing root tip cells of the gymnosperm Abies cephalonica Loudon were investigated by confocal laser scanning microscopy after tubulin and endoplasmic reticulum immunolocalization and DNA staining.
Ioannis-Dimosthenis S. Adamakis, Emmanuel Panteris, Eleftherios P. Eleftheriou   +2 more
openaire   +3 more sources

Short exposure to paclitaxel induces multipolar spindle formation and aneuploidy through promotion of acentrosomal pole assembly

Science China Life Sciences, 2010
Paclitaxel is a widely used microtubule drug and cancer medicine. Here we report that by short exposure to paclitaxel at a low dose, multipolar spindles were induced in mitotic cells without centrosome amplification. Both TPX2 depletion and Aurora-A overexpression antagonized the multipolarity.
Jingyan Fu, Chuanmao Zhang, Yan Yan, Qing Jiang, Minglei Bian, QingHua Shi, Qiang Chen, Chao Yang   +7 more
openaire   +3 more sources

Faculty Opinions recommendation of Spindle multipolarity is prevented by centrosomal clustering.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2005
Stephen Doxsey
openalex   +2 more sources

Induction of multiple microtubule-organizing centers, multipolar spindles and multipolar division in cultured V79 cells exposed to diethylstilbestrol, estradiol-17β and bisphenol A

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1999
Inducibility of multipolar spindles and multipolar division by diethylstilbestrol (DES) and estradiol-17beta (E2) was investigated in terms of the mechanism of induction of aneuploidy by the estrogens. DES, E2 and bisphenol A (Bp-A), a structural analogue of DES, caused mitotic arrest and aberrant spindles, such as tripolar and multipolar spindles, in ...
openaire   +3 more sources

Abstract 1849: Determining the molecular requirements for paclitaxel-induced spindle multipolarity

Cancer Research, 2018
Abstract Paclitaxel (TaxolTM) and other microtubule poisons are standard chemotherapy agents used in the treatment of breast cancer. However, only a subset of patients experience positive therapeutic effects from these drugs, underscoring the importance of further mechanistic study.
openaire   +2 more sources

Role of mitotic motors, dynein and kinesin, in the induction of abnormal centrosome integrity and multipolar spindles in cultured V79 cells exposed to dimethylarsinic acid

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2002
The role of microtubule-based motors in the induction of abnormal centrosome integrity by dimethylarsinic acid (DMAA) was investigated with the use of monastrol, a specific inhibitor of mitotic kinesin, and vanadate, an inhibitor of dynein ATPase. Cytoplasmic dynein co-localized with multiple foci of gamma-tubulin in mitotic cells arrested by DMAA ...
Takafumi Ochi
openalex   +4 more sources

Induction of multipolar spindle in Allium sativum.

Cytobios, 1979
The effect of the polyene antifungal antibiotic aureofungin on the chromosomes of Allium sativum was examined. Mitotic studies showed chromosomal abnormalities of metaphase and anaphase. Besides these anomalies, the alteration of the spindle, i.e. tri- to multipolar condition, was also observed in treatment with 100 microgram treatment for 24 h, and ...
P, Kumar, K, Leela, P, Laxminarayana, J, Nizam   +3 more
openaire   +1 more source

Pineal cells with multipolar spindles in chicken embryos exposed to magnetic fields--first trials.

Zeitschrift fur mikroskopisch-anatomische Forschung, 1986
Bardasano Jl, Meyer Aj, L Picazo
openalex   +2 more sources