Results 141 to 150 of about 153,409 (229)

The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle [PDF]

, 2015
Kinetochore fibers (K-fibers) of the mitotic spindle are force-generating units that power chromosome movement during mitosis. K-fibers are composed of many microtubules that are held together throughout their length.
Booth, Daniel G., Gutierrez-Caballero, Cristina, Hood, Fiona E., Nixon, Faye M., Prior, Ian A., Royle, Stephen J.   +5 more
core   +3 more sources

Loss of CHFR in Human Mammary Epithelial Cells Causes Genomic Instability by Disrupting the Mitotic Spindle Assembly Checkpoint

Neoplasia: An International Journal for Oncology Research, 2008
CHFR is an E3 ubiquitin ligase and an early mitotic checkpoint protein implicated in many cancers and in the maintenance of genomic stability. To analyze the role of CHFR in genomic stability, by siRNA, we decreased its expression in genomically stable ...
Lisa M. Privette, Jingly Fung Weier, Ha Nam Nguyen, Xiaochun Yu, Elizabeth M. Petty   +4 more
doaj   +1 more source

Cyclin d1 induces chromosomal instability. [PDF]

, 2012
We developed mouse model systems to investigate the potential for cyclin D1 to induce CIN in vivo. In a mammary gland specific Tet-inducible model the acute expression profile regulated by cyclin D1 after 7 days was enriched in genes that rank highly ...
Casimiro, Mathew C, Pestell, Richard
core   +1 more source

Deoxynivalenol triggers mitotic catastrophe and apoptosis in C2C12 myoblasts

Ecotoxicology and Environmental Safety
Deoxynivalenol (DON), commonly known as vomitoxin, is a mycotoxin produced by fungi and is frequently found as a contaminant in various cereal-based food worldwide.
Zhenzhen Wang, Huimin Duan, Xue You, Qian Peng, Ningyang Yuan, Rula Sha, Zhiqin Xie, Ying Feng   +7 more
doaj   +1 more source

Abstracts

Cancer Science, Volume 117, Issue S1, Page 1-2148, January 2026.
wiley   +1 more source

Nerve Tissue [PDF]

, 2009
Histology blog entry for January 6, 2009 about nerve ...
Krause, William J., II, 1942-
core  

When the Genome Plays Dice: Circumvention of the Spindle Assembly Checkpoint and Near-Random Chromosome Segregation in Multipolar Cancer Cell Mitoses

, 2008
David Gisselsson, Ulf Håkanson, Patrick Stoller, Dominik Marti, Yuesheng Jin, Anders H. Rosengren, Ylva Stewénius, Fredrik Kahl, Ioannis Panagopoulos   +8 more
openalex   +2 more sources

The Arabidopsis ATK1 gene is required for spindle morphogenesis in male meiosis [PDF]

, 2002
The spindle plays a central role in chromosome segregation during mitosis and meiosis. In particular, various kinesins are thought to play crucial roles in spindle structure and function in both mitosis and meiosis of fungi and animals.
Calzada, J. P. V., Chen, C. B., Cyr, R. J., Grossniklaus, U., Hu, Y., Li, W. X., Ma, H., Marcus, A.   +7 more
core  

Improving treatment of glioblastoma: new insights in targeting cancer stem cells effectively [PDF]

, 2015
Glioblastoma is the most common primary malignant brain tumour in the adult population. Despite multimodality treatment with surgery, radiotherapy and chemotherapy, outcomes are very poor, with less than 15% of patients alive after two years ...
Mannino, Mariella
core  

A Clinical Overview of Centrosome Amplification in Human Cancers

International Journal of Biological Sciences, 2011
The turn of the 21st century had witnessed a surge of interest in the centrosome and its causal relation to human cancer development - a postulate that has existed for almost a century.
Jason Yongsheng Chan
doaj