Results 231 to 240 of about 61,024 (262)

C6orf223 promotes colorectal cancer growth and metastasis by facilitating PRMT5-MEP50 multiprotein complex assembling. [PDF]

open access: yesJ Clin Invest
Qiao Y   +20 more
europepmc   +1 more source

Baculovirus expression system for heterologous multiprotein complexes

Nature Biotechnology, 2004
The discovery of large multiprotein complexes in cells has increased the demand for improved heterologous protein production techniques to study their molecular structure and function. Here we describe MultiBac, a simple and versatile system for generating recombinant baculovirus DNA to express protein complexes comprising many subunits.
Imre Berger
exaly   +3 more sources

Multiprotein complexes governing Wnt signal transduction

Current Opinion in Cell Biology, 2018
Three multiprotein complexes have key roles in transducing Wnt signals from the plasma membrane to the cell nucleus - the β-catenin destruction complex, or Axin degradasome, which targets the Wnt effector β-catenin for proteasomal degradation in the absence of Wnt; the Wnt signalosome, assembled by polymerization of Dishevelled upon Wnt engaging its ...
Melissa V Gammons, Mariann Bienz
exaly   +3 more sources

MULTIPROTEIN-DNA COMPLEXES IN TRANSCRIPTIONAL REGULATION

Annual Review of Biophysics and Biomolecular Structure, 1999
▪ Abstract  Transcription in eukaryotes is frequently regulated by a mechanism termed combinatorial control, whereby several different proteins must bind DNA in concert to achieve appropriate regulation of the downstream gene. X-ray crystallographic studies of multiprotein complexes bound to DNA have been carried out to investigate the molecular ...
Cynthia Wolberger
exaly   +3 more sources

Proteomics of multiprotein complexes: answering fundamental questions in neuroscience

Trends in Biotechnology, 2001
Proteomics tools offer new ways to analyse networks of proteins that control important neurobiological phenomena such as learning and memory. In this review, we discuss how a combined proteomic, pharmacological and genetic approach reveals that multiprotein complexes process neural information and encode memories.
Seth G Grant, Holger Husi
exaly   +3 more sources

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