Results 31 to 40 of about 40,419 (211)
Poxvirus multiprotein entry–fusion complex [PDF]
Proceedings of the National Academy of Sciences, 2005 Poxviruses have evolved elaborate mechanisms for cell entry, assembly, and exocytosis. Recently, four vaccinia virus membrane proteins, namely A21, A28, H2 and L5, were reported to be necessary for cell entry and virus-induced cell–cell fusion but not for virion morphogenesis or attachment of virus particles to cells.
Tatiana G, Senkevich +4 more
openaire +2 more sources
Quis Custodiet Ipsos Custodes (Who Controls the Controllers)? Two Decades of Studies on HDAC9
Life, 2021 Understanding how an epigenetic regulator drives different cellular responses can be a tricky task. Very often, their activities are modulated by large multiprotein complexes, the composition of which is context- and time-dependent.
Claudio Brancolini +3 more
doaj +1 more source
Identification and analysis of multi-protein complexes in placenta. [PDF]
PLoS ONE, 2013 Placental malfunction induces pregnancy disorders which contribute to life-threatening complications for both the mother and the fetus. Identification and characterization of placental multi-protein complexes is an important step to integratedly ...
Fuqiang Wang +3 more
doaj +1 more source
Role of Endoplasmic Reticulum-Associated Proteins in Flavivirus Replication and Assembly Complexes
Pathogens, 2019 Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins.
Hussin A. Rothan, Mukesh Kumar
doaj +1 more source
Nature Communications, 2020 Eukaryotic replisomes are multiprotein complexes. Here the authors reveal two distinct stressed replisomes, associated with DONSON and FANCM, displaying a bias in replication timing and chromatin domain.
Jing Zhang +9 more
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Virtual and biophysical screening targeting the γ-tubulin complex--a new target for the inhibition of microtubule nucleation. [PDF]
PLoS ONE, 2013 Microtubules are the main constituents of mitotic spindles. They are nucleated in large amounts during spindle assembly, from multiprotein complexes containing γ-tubulin and associated γ-tubulin complex proteins (GCPs).
Olivier Cala +6 more
doaj +1 more source
The role of salt bridges, charge density, and subunit flexibility in determining disassembly routes of protein complexes [PDF]
, 2013 Mass spectrometry can be used to characterize multiprotein complexes, defining their subunit stoichiometry and composition following solution disruption and collision-induced dissociation (CID).
Marsh, J +15 more
core +1 more source
The inner workings of the hydrazine synthase multiprotein complex [PDF]
Nature, 2015 Anaerobic ammonium oxidation (anammox) has a major role in the Earth's nitrogen cycle and is used in energy-efficient wastewater treatment. This bacterial process combines nitrite and ammonium to form dinitrogen (N2) gas, and has been estimated to synthesize up to 50% of the dinitrogen gas emitted into our atmosphere from the oceans.
Andreas Dietl +8 more
openaire +5 more sources
Cells, 2020 The aberrant function of chromatin regulatory networks (epigenetics) is a hallmark of cancer promoting oncogenic gene expression. A growing body of evidence suggests that the disruption of specific chromatin-associated protein complexes has therapeutic ...
Florian Perner, Scott A. Armstrong
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Assembly and regulation of γ-tubulin complexes [PDF]
Open Biology, 2018 Microtubules are major constituents of the cytoskeleton in all eukaryotic cells. They are essential for chromosome segregation during cell division, for directional intracellular transport and for building specialized cellular structures such as cilia or
Dorian Farache +3 more
doaj +1 more source