Results 21 to 30 of about 960,142 (193)

Role of Endoplasmic Reticulum-Associated Proteins in Flavivirus Replication and Assembly Complexes

open access: yesPathogens, 2019
Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins.
Hussin A. Rothan, Mukesh Kumar
doaj   +1 more source

DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain

open access: yesNature Communications, 2020
Eukaryotic replisomes are multiprotein complexes. Here the authors reveal two distinct stressed replisomes, associated with DONSON and FANCM, displaying a bias in replication timing and chromatin domain.
Jing Zhang   +9 more
doaj   +1 more source

Identification and analysis of multi-protein complexes in placenta. [PDF]

open access: yesPLoS ONE, 2013
Placental malfunction induces pregnancy disorders which contribute to life-threatening complications for both the mother and the fetus. Identification and characterization of placental multi-protein complexes is an important step to integratedly ...
Fuqiang Wang   +3 more
doaj   +1 more source

The role of salt bridges, charge density, and subunit flexibility in determining disassembly routes of protein complexes [PDF]

open access: yes, 2013
Mass spectrometry can be used to characterize multiprotein complexes, defining their subunit stoichiometry and composition following solution disruption and collision-induced dissociation (CID).
Marsh, J   +15 more
core   +1 more source

Bound Cations Significantly Stabilize the Structure of Multiprotein Complexes in the Gas Phase [PDF]

open access: yesAngewandte Chemie - International Edition, 2012
Suk-Joon Hyung   +2 more
exaly   +2 more sources

Transcription factor GATA-1-multiprotein complexes and chicken erythroid development [PDF]

open access: yes, 1994
The chicken erythrocyte transcription factor, GATA-1, is associated with several non-DNA binding proteins. We show that GATA-1 multiprotein complexes exist in primitive and definitive erythrocytes.
Davie, James R.   +3 more
core   +1 more source

Targeting Chromatin Complexes in Myeloid Malignancies and Beyond: From Basic Mechanisms to Clinical Innovation

open access: yesCells, 2020
The aberrant function of chromatin regulatory networks (epigenetics) is a hallmark of cancer promoting oncogenic gene expression. A growing body of evidence suggests that the disruption of specific chromatin-associated protein complexes has therapeutic ...
Florian Perner, Scott A. Armstrong
doaj   +1 more source

Assembly and regulation of γ-tubulin complexes [PDF]

open access: yesOpen Biology, 2018
Microtubules are major constituents of the cytoskeleton in all eukaryotic cells. They are essential for chromosome segregation during cell division, for directional intracellular transport and for building specialized cellular structures such as cilia or
Dorian Farache   +3 more
doaj   +1 more source

Fine-Tuning Multiprotein Complexes Using Small Molecules [PDF]

open access: yes, 2012
Multiprotein complexes such as the transcriptional machinery, signaling hubs, and protein folding machines are typically composed of at least one enzyme combined with multiple non-enzymes.
Mapp, Anna K   +3 more
core   +1 more source

SmartBac, a new baculovirus system for large protein complex production

open access: yesJournal of Structural Biology: X, 2019
Recent revolution of cryo-electron microscopy has opened a new door to solve high-resolution structures of macromolecule complexes without crystallization while how to efficiently obtain homogenous macromolecule complex sample is therefore becoming a ...
Yujia Zhai   +4 more
doaj   +1 more source

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