Structure-Based Characterization of Multiprotein Complexes [PDF]
Structure, 2014 Multiprotein complexes govern virtually all cellular processes. Their 3D structures provide important clues to their biological roles, especially through structural correlations among protein molecules and complexes.
Markus Wiederstein +2 more
exaly +8 more sources
MultiBac: expanding the research toolbox for multiprotein complexes [PDF]
Trends in Biochemical Sciences, 2012 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Christoph Bieniossek +2 more
exaly +7 more sources
Assembly of multiprotein complexes that control genome function [PDF]
Journal of Cell Biology, 2009 Live-cell imaging studies aided by mathematical modeling have provided unprecedented insight into assembly mechanisms of multiprotein complexes that control genome function.
Christoffel Dinant +2 more
exaly +10 more sources
Ion channels as part of macromolecular multiprotein complexes : Clinical significance. [PDF]
Herzschrittmacherther Elektrophysiol, 2018 Ion channels and Ca2+-handling proteins involved in the regulation of cardiac electrophysiology and contractility are organized in macromolecular multiprotein complexes.
Heijman J, Dobrev D.
europepmc +5 more sources
Exploring the Complexity of Protein-Level Dosage Compensation that Fine-Tunes Stoichiometry of Multiprotein Complexes. [PDF]
PLoS Genet, 2020 Proper control of gene expression levels upon various perturbations is a fundamental aspect of cellular robustness. Protein-level dosage compensation is one mechanism buffering perturbations to stoichiometry of multiprotein complexes through accelerated ...
Ishikawa K, Ishihara A, Moriya H.
europepmc +3 more sources
Very Stable High-Molecular-Mass Multiprotein Complexes in Different Organs of the Sea Cucumber Paracaudina chilensis [PDF]
MoleculesWe report the first identification of several large (1.4–2.2 MDa), highly stable protein–peptide complexes in various organs and tissues (body wall, gonads, respiratory trees, gut, and coelomic fluid) of the sea cucumber Paracaudina chilensis.
Svetlana E. Soboleva +5 more
doaj +2 more sources
Biological Procedures Online, 2002 There is accumulating evidence that membrane-bound receptors interact with many intracellular proteins. Multiprotein complexes associated with ionotropic receptors have been extensively characterized, but the identification of proteins interacting with G
Bécamel Carine +6 more
doaj +2 more sources
Multiprotein Complexes of Plant Glycosyltransferases Involved in Their Function and Trafficking [PDF]
PlantsPlant cells utilize protein oligomerization for their functions in numerous important cellular processes. Protein-protein interactions are necessary to stabilize, optimize, and activate enzymes, as well as localize proteins to specific organelles and ...
Ning Zhang +2 more
doaj +2 more sources
Two binding sites are better than one [PDF]
eLifeThe reasons why two multiprotein complexes – VPS34 complex I and VPS34 complex II – are activated by different Rab proteins are becoming clearer.
Mackenzie K Scott, John E Burke
doaj +2 more sources
Proteomics of multiprotein complexes: answering fundamental questions in neuroscience
Trends in Biotechnology, 2001 Proteomics tools offer new ways to analyse networks of proteins that control important neurobiological phenomena such as learning and memory. In this review, we discuss how a combined proteomic, pharmacological and genetic approach reveals that ...
Seth G N Grant
exaly +2 more sources