MultiBac: expanding the research toolbox for multiprotein complexes. [PDF]
Trends Biochem Sci, 2012 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Bieniossek C +3 more
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Assembly of multiprotein complexes that control genome function. [PDF]
J Cell Biol, 2009 Live-cell imaging studies aided by mathematical modeling have provided unprecedented insight into assembly mechanisms of multiprotein complexes that control genome function. Such studies have unveiled emerging properties of chromatin-associated systems involved in DNA repair and transcription.
Dinant C +6 more
europepmc +11 more sources
Ion channels as part of macromolecular multiprotein complexes : Clinical significance. [PDF]
Herzschrittmacherther Elektrophysiol, 2018 Ion channels and Ca2+-handling proteins involved in the regulation of cardiac electrophysiology and contractility are organized in macromolecular multiprotein complexes. Recent molecular and cellular studies have significantly enhanced our understanding of the composition of these macromolecular complexes and have helped to elucidate their role in the ...
Heijman J, Dobrev D.
europepmc +5 more sources
Very Stable High-Molecular-Mass Multiprotein Complexes in Different Organs of the Sea Cucumber Paracaudina chilensis [PDF]
MoleculesWe report the first identification of several large (1.4–2.2 MDa), highly stable protein–peptide complexes in various organs and tissues (body wall, gonads, respiratory trees, gut, and coelomic fluid) of the sea cucumber Paracaudina chilensis.
Svetlana E. Soboleva +5 more
doaj +2 more sources
Two binding sites are better than one [PDF]
eLifeThe reasons why two multiprotein complexes – VPS34 complex I and VPS34 complex II – are activated by different Rab proteins are becoming clearer.
Mackenzie K Scott, John E Burke
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Multiprotein Complexes of Plant Glycosyltransferases Involved in Their Function and Trafficking [PDF]
PlantsPlant cells utilize protein oligomerization for their functions in numerous important cellular processes. Protein-protein interactions are necessary to stabilize, optimize, and activate enzymes, as well as localize proteins to specific organelles and ...
Ning Zhang +2 more
doaj +2 more sources
Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence [PDF]
Cell Reports, 2017 Arc is an activity-regulated neuronal protein, but little is known about its interactions, assembly into multiprotein complexes, and role in human disease and cognition.
Esperanza Fernández +22 more
doaj +9 more sources
Multicolour fluorescence-detection size-exclusion chromatography for structural genomics of membrane multiprotein complexes. [PDF]
PLoS ONE, 2013 Many interesting and important membrane proteins are hetero-oligomeric. However, besides naturally abundant examples, the structures of relatively few such complexes are known.
David Parcej +4 more
doaj +2 more sources
Modulation of Nudt21 levels reveals dose-dependent roles of alternative polyadenylation in tissue regeneration [PDF]
Nature CommunicationsStem cells continually self-renew and differentiate to sustain tissue homeostasis, yet the role of post-transcriptional mechanisms in guiding these processes remains incompletely understood.
Nikolaos Tsopoulidis +19 more
doaj +2 more sources
Equi‐MOI ratio for rapid baculovirus‐mediated multiprotein co‐expression in insect cells integrating selenomethionine for structural studies [PDF]
FEBS Open BioProteins often co‐exist as multicomponent assemblies, making their co‐expression essential in recombinant production processes. The baculovirus expression vector system is commonly used to produce recombinant multiprotein complexes mostly for structural ...
Andrej Bitala +3 more
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