Results 11 to 20 of about 9,030 (299)
Multivalency influences virus dynamics at the glycocalyx : a study of glycosaminoglycan binding in HPV16 entry [PDF]
Biophys JVirus attachment at the cell surface often involves the establishment of multiple ligand-receptor interactions between viral capsid proteins and glycans in the glycocalyx. Multivalency likely contributes to strengthening and fine-tuning virus dynamics at
Seier, Kerstin +17 more
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Entropy-Driven Physical Amplification in Multivalent Biosensing. [PDF]
Adv Sci (Weinh)Detecting scarce molecules usually demands enzymatic amplification such as PCR. A statistical‐mechanical theory now reveals a purely physical alternative: distributing a fixed binding strength over more linker arms exponentially lowers the concentration at which multivalent sensors switch on.
Peng Y, Xia X, Ni R.
europepmc +2 more sources
, 2017 Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced ...
openaire +2 more sources
Polymer Concepts in Cellular Function. [PDF]
Adv Sci (Weinh)Advanced Science, EarlyView.
Yu M +7 more
europepmc +2 more sources
Enhanced Diffusion through Multivalency
Soft Matter, 2023 Abstract In multivalent systems, multiple ligands from one entity simultaneously bind to multiple receptors on another entity. These interactions are of crucial significance in a wide range of biological and technological mechanisms, encompassing selectivity, host recognition, viral penetration, therapeutic delivery, as well as the ...
Ladislav Bartoš +2 more
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DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition [PDF]
Advanced ScienceThe rapid evolution and antigenic diversity of influenza A viruses (IAVs) continue to challenge antiviral strategies, highlighting the need for broadly effective and modular therapeutic platforms.
Saurabh Umrao +8 more
doaj +2 more sources
Multivalency Pattern Recognition to Sort Colloidal Assemblies [PDF]
, 2020 Multivalent interactions are an important principle for self-assembly, and have been widely used to assemble colloidal systems. However, binding partners on colloids are typically statistically distributed, which falls short of the possibilities arising ...
Sebastian, Loescher, Andreas, Walther
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Multivalent Diffusive Transport [PDF]
The Journal of Physical Chemistry B, 2021 We present here a model for multivalent diffusive transport whereby a central point-like hub is coupled to multiple feet, which bind to complementary sites on a two-dimensional landscape. The available number of binding interactions is dependent on the number of feet (multivalency), and on their allowed distance from the central hub (span). Using Monte
Antonia Kowalewski +2 more
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On Certain Multivalent Functions [PDF]
International Journal of Mathematics and Mathematical Sciences, 2007 Let𝒮*(p,α)be the class of functionsf(z)which are analytic andp-valently starlike of orderαin the open unit diskE. The object of the present paper is to derive an interesting condition forf(z)to be in the class𝒮*(p,α).
Mamoru Nunokawa +5 more
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, 2022 The size of membrane-enveloped virus particles, exosomes, and lipid vesicles strongly impacts functional properties in biological and applied contexts. Multivalent ligand–receptor interactions involving nanoparticle shape deformation are critical to such
Hyeonjin Park (11138244) +13 more
core +1 more source