Results 41 to 50 of about 297,008 (317)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Discrete-Time Inverted Decoupling Internal Model Control of Multivariable Systems Based on Improved Fractional-Order Butterworth Filter

open access: yesIEEE Access
A novel discrete-time inverted decoupling internal model control (IMC) strategy is proposed for discrete-time multivariable systems with time-delays and RHP zeros.
Kaiyue Liu   +5 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Multivariable predictive controller for a test stand of air conditionning [PDF]

open access: yes, 1997
In this paper a Multivariable Predictive Controller has been proposed in a stochastic framework for a M-input N-output system. It has been investigated using a simulation study based on an experimental model of an industrial test stand of air ...
Vaucoret, Cyril   +1 more
core  

From Reflectory Ring to Multivariable System [PDF]

open access: yesPsychology in Russia: State of Art, 2009
Some special features of feedback functioning in live movement control are discussed. Taking into account the multicoupling nerve structure of movement apparatus we inevitable are faced with a question about principles based in clousing of chanals ...
Аnatoly I. Nazarov
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Nonlinear system-identification of the filling phase of a wet-clutch system [PDF]

open access: yes, 2011
The work presented illustrates how the choice of input perturbation signal and experimental design improves the derived model of a nonlinear system, in particular the dynamics of a wet-clutch system.
Widanage, Widanalage Dhammika   +9 more
core   +1 more source

Virtual Laboratory Attended with Matlab for the Multivariable Industrial System

open access: yesRevista Cubana de Ingeniería, 2010
In this paper the authors present and discuss results obtained from on the conformation of a practice of virtual laboratory attended with Matlab, for the design of a multivariavels controller for a distillation column.
Daniel Guzmán del Río   +3 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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