Results 221 to 230 of about 9,714,861 (297)

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Risk stratification for stroke in acute persistent vertigo: development and internal validation of a multivariable prediction model. [PDF]

Front Neurol
Ba Y, Liu B, Zhu P.
europepmc   +1 more source

Improved Skills for Predicting Sub‐Seasonal to Seasonal Global Sea Surface Temperature

Advanced Science, EarlyView.
Addressing the critical Sub‐seasonal to Seasonal predictability gap, this study presents CAS‐Canglong, a novel deep learning framework. By leveraging 3D Swin‐Transformers to capture long‐range ocean interactions, the model demonstrates superior skill over traditional GCMs.
Longhao Wang, Xuanze Zhang, Ruby L. Leung, Francis H. S. Chiew, Amir AghaKouchak, Kairan Ying, Yongqiang Zhang   +6 more
wiley   +1 more source

Association of stroke unit certification with process quality in acute ischemic stroke: a registry-based study. [PDF]

Neurol Res Pract
Boehl M, Geraedts M, Ji L, Misselwitz B, Neumann-Haefelin T.   +4 more
europepmc   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Reduced susceptibility to triclosan and proposed epidemiological cut-off values for disinfectants and heavy metals in Escherichia coli isolated from Thai tilapia farms: Implications for One Health antimicrobial resistance surveillance. [PDF]

Vet World
Thaotumpitak V, Sripradite J, Anuntawirun S, Roongrojmongkhon N, Hinthong W, Jeamsripong S.   +5 more
europepmc   +1 more source

An Explainable Multimodal Deep‐Learning Model Using Histopathological Image and Clinical Information for Prognosis Prediction in Colorectal Cancer: A Multi‐Center Cohort Study

Advanced Science, EarlyView.
This study develops a multimodal deep‐learning model that integrates clinical variables and histopathological images to predict survival outcomes in colorectal cancer. The multimodal model effectively stratifies patients into low‐ and high‐risk groups, demonstrating superior accuracy and generalizability across multiple independent cohorts.
Zhihan Jiang, Xiangchao Shi, Chenghan Su, Yao Ma, Rui Li, Menglei Chen, Jianxin Cui, Nicholas Hawkins, Robyn Ward, Xiangzhi Bai, Jitendra Jonnagaddala, Wei Fu, Xin Zhou   +12 more
wiley   +1 more source

Seroprevalence and Associated Risk Factors of Foot-and-Mouth Disease in Livestock in Ethiopia: Findings From a National Surveillance (2016-2023). [PDF]

Vet Med Sci
Gizaw D, Asgdom H, Muluneh A, Fentie A, Negessu D, Bogale G, Worku T, Abebe A, Mekonnen GA.   +8 more
europepmc   +1 more source

Endoscopic evacuation of spontaneous intracerebral hemorrhage: Surgical outcomes and prognostic factors. [PDF]

Surg Neurol Int
Gupta V, Gupta P.
europepmc   +1 more source