Results 41 to 50 of about 37,167 (216)
Traffic into silence: endomembranes and post-transcriptional RNA silencing. [PDF]
, 2014 microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-
Chen, Xuemei +2 more
core +3 more sources
Cycling of dense core vesicles involved in somatic exocytosis of serotonin by leech neurons
Frontiers in Physiology, 2012 We studied the cycling of dense core vesicles producing somatic exocytosis of serotonin. Our experiments were made using electron microscopy and vesicle staining with fluorescent dye FM1-43 in Retzius neurons of the leech, which secrete serotonin from ...
Citlali eTrueta +2 more
doaj +1 more source
Isoform-specific targeting of PKA to multivesicular bodies. [PDF]
J Cell Biol, 2011 Although RII protein kinase A (PKA) regulatory subunits are constitutively localized to discrete cellular compartments through binding to A-kinase–anchoring proteins (AKAPs), RI subunits are primarily diffuse in the cytoplasm. In this paper, we report a novel AKAP-dependent localization of RIα to distinct organelles, specifically, multivesicular bodies
Day ME +8 more
europepmc +4 more sources
Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region [PDF]
, 2017 The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases.
De Pablos, Luis Miguel +5 more
core +3 more sources
Journal of Limnology, 2013 The aims of our studies were to describe the ultrastructure of the midgut epithelial cells of the eutardigrade Xerobiotus pseudohufelandi and to determine if there are any differences in the ultrastructure of midgut epithelial cells between males and ...
Magdalena M. Rost-Roszkowska +4 more
doaj +1 more source
Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine [PDF]
, 2012 The neonatal Fc receptor (FcRn) transports maternal immunoglobulin (IgG) across epithelia to confer passive immunity to mammalian young. In newborn rodents, FcRn transcytoses IgG from ingested milk across the intestinal epithelium for release into the ...
Bjorkman, Pamela J. +2 more
core +2 more sources
Secretory Granule Membrane Protein Recycles through Multivesicular Bodies [PDF]
Traffic, 2010 The recycling of secretory granule membrane proteins that reach the plasma membrane following exocytosis is poorly understood. As a model, peptidylglycine alpha-amidating monooxygenase (PAM), a granule membrane protein that catalyzes a final step in peptide processing was examined.
Nils, Bäck +3 more
openaire +2 more sources
Human endothelial progenitor cells internalize high-density lipoprotein.
PLoS ONE, 2013 Endothelial progenitor cells (EPCs) originate either directly from hematopoietic stem cells or from a subpopulation of monocytes. Controversial views about intracellular lipid traffic prompted us to analyze the uptake of human high density lipoprotein ...
Kaemisa Srisen +6 more
doaj +1 more source
Antioxidants, 2021 To investigate the role of NLRP3 inflammasome in cardiac aging, we evaluate here morphological and ultrastructural age-related changes of cardiac muscles fibers in wild-type and NLRP3-knockout mice, as well as studying the beneficial effect of melatonin ...
Ramy K. A. Sayed +9 more
doaj +1 more source
The Multivesicular Body and Autophagosome Pathways in Plants [PDF]
Frontiers in Plant Science, 2018 In eukaryotic cells, the endomembrane system consists of multiple membrane-bound organelles, which play essential roles in the precise transportation of various cargo proteins. In plant cells, vacuoles are regarded as the terminus of catabolic pathways whereas the selection and transport of vacuolar cargoes are mainly mediated by two types of ...
Yong Cui +10 more
openaire +3 more sources