Exosomes: a novel therapeutic target for Alzheimer’s disease?
Neural Regeneration Research, 2018 Extracellular exosomes are formed inside the cytoplasm of cells in compartments known as multivesicular bodies. Thus, exosomes contain cytoplasmic content.
Zhi-You Cai +3 more
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Chlamydial infection from outside to inside [PDF]
, 2019 Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke +2 more
core +2 more sources
Seed-produced anti-globulin VHH-Fc antibodies retrieve globulin precursors in the insoluble fraction and modulate the Arabidopsis thaliana seed subcellular morphology [PDF]
, 2020 Key message Nanobody-heavy chain (VHH-Fc) antibody formats have the potential to immunomodulate even highly accumulating proteins and provide a valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.
Altmann, Friedrich +7 more
core +2 more sources
Autophagy and multivesicular bodies: two closely related partners [PDF]
Cell Death & Differentiation, 2008 In the majority of cell types, multivesicular bodies (MVBs) are a special kind of late endosomes, crucial intermediates in the internalization of nutrients, ligands and receptors through the endolysosomal system. ESCRT-0, I, II and III (endosomal sorting complex required for transport) are involved in the sorting of proteins into MVBs, generating the ...
C M, Fader, M I, Colombo
openaire +2 more sources
Plant Exosomal Vesicles: Perspective Information Nanocarriers in Biomedicine
Applied Sciences, 2022 Exosomal nanoparticles (exosomes or nanovesicles) are biogenic membrane vesicles secreted by various cell types and represent a conservative mechanism of intercellular and interspecies communication in pro- and eukaryotic organisms.
Yury Shkryl +6 more
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Late Endosomes: Sorting and Partitioning in Multivesicular Bodies [PDF]
Traffic, 2001 Late endosomes, which have the morphological characteristics of multivesicular bodies, have received relatively little attention in comparison with early endosomes and lysosomes. Recent work in mammalian and yeast cells has given insights into their structure and function, including the generation of their multivesicular morphology.
R C, Piper, J P, Luzio
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TPLATE recruitment reveals endocytic dynamics at sites of symbiotic interface assembly in arbuscular mycorrhizal interactions [PDF]
, 2019 Introduction: Arbuscular mycorrhizal (AM) symbiosis between soil fungi and the majority of plants is based on a mutualistic exchange of organic and inorganic nutrients.
Bonfante, Paola +9 more
core +3 more sources
The role of surface charge in the interaction of nanoparticles with model pulmonary surfactants [PDF]
, 2018 Inhaled nanoparticles traveling through the airways are able to reach the respiratory zone of the lungs. In such event, the incoming particles first enter in contact with the liquid lining the alveolar epithelium, the pulmonary surfactant.
Berret, J. -F., Mousseau, F.
core +4 more sources
Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse [PDF]
, 2003 We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket ...
Dean, I., Edwards, F.A., Robertson, S.J.
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eLifeRecent studies showed an unexpected complexity of extracellular vesicle (EV) biogenesis pathways. We previously found evidence that human colorectal cancer cells in vivo release large multivesicular body-like structures en bloc.
Tamás Visnovitz +14 more
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