Combining genomics and epidemiology to track mumps virus transmission in the United States. [PDF]
Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks.
Wohl S+29 more
europepmc +5 more sources
Exploring the Mumps Virus Glycoproteins: A Review. [PDF]
The resurgence of mumps in vaccinated adult populations has raised concerns about possible waning vaccine immunity or a potential lack of protection to the circulating strain. A number of individual studies have investigated if there are amino acid variations between the circulating wild-type strains and vaccine strains.
Frost JR, Shaikh S, Severini A.
europepmc +4 more sources
Oligomerization of Mumps Virus Phosphoprotein [PDF]
ABSTRACT The mumps virus (MuV) genome encodes a phosphoprotein (P) that is important for viral RNA synthesis. P forms the viral RNA-dependent RNA polymerase with the large protein (L). P also interacts with the viral nucleoprotein (NP) and self-associates to form a homotetramer.
Pei Xu+5 more
openaire +3 more sources
Polypeptides of mumps virus [PDF]
Mumps virus was propagated in the extra-embryonic fluids of embryonated chicken eggs and was labeled by cionjection of radioactively labeled amino acids. The virus was purified by density gradient centrifugation, and its polypeptides were analyzed by polyarylamide gel electrophoresis.
S Silver, S C Jensik
openaire +2 more sources
Mumps vaccine failure investigation in Novosibirsk, Russia, 2002–2004 [PDF]
The aims of this study were to estimate the importance of vaccine failure (VF) in cases of mumps during 2002–2004 in the city of Novosibirsk, Western Siberia, Russia, and to genotype the responsible virus strain.
Atrasheuskaya, A.V.+3 more
core +1 more source
No association between islet cell antibodies and coxsackie B, mumps, rubella and cytomegalovirus antibodies in non-diabetic individuals aged 7–19 years [PDF]
Viral antibodies were tested in a cohort of 44 isletcell antibody-positive individuals age 7–19 years, and 44 of their islet cell antibody-negative age and sex-matched classmates selected from a population study of 4208 pupils who had been screened for ...
A Tarn+32 more
core +1 more source
Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens. [PDF]
The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions.
Crawford, Emily D.+25 more
core +2 more sources
A HEMOLYSIN ASSOCIATED WITH THE MUMPS VIRUS [PDF]
1. A factor capable of causing the hemolysis of the erythrocytes of man, chicken, and sheep occurs in the amniotic and allantoic fluids of chick embryos infected with the virus of mumps. 2. The hemolysin has not been found in normal fluids or in those infected with PR8 or Lee B strains of influenza virus. 3.
Philip F. Wagley+2 more
openaire +3 more sources
2019-nCoV: The Identify-Isolate-Inform (3I) Tool Applied to a Novel Emerging Coronavirus [PDF]
2019 Novel Coronavirus (2019-nCoV) is an emerging infectious disease closely related to MERS-CoV and SARS-CoV that was first reported in Wuhan City, Hubei Province, China in December 2019.
Bey, Christian K.+2 more
core +1 more source
The Mumps Virus Neurovirulence Safety Test in Rhesus Monkeys:A Comparison of Mumps Virus Strains [PDF]
Wild type mumps viruses are highly neurotropic and a frequent cause of aseptic meningitis in unvaccinated humans. To test whether attenuated mumps viruses used in the manufacture of mumps vaccines have neurovirulent properties, a monkey neurovirulence safety test (MNVT) is performed. However, results with several mumps virus MNVTs have raised questions
Earl G. Brown+6 more
openaire +3 more sources