Glycosylation as a strategic mechanism for measles virus and mumps virus immune evasion [PDF]
Frontiers in ImmunologyGlycosylation of viral surface proteins by host cell factors is one strategy paramyxoviruses employ to evade the host’s immune system during infection. Viral glycosylation thus has the potential for innate and adaptive immune modulation.
Catalina Galvan +2 more
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Genetic characteristic of mumps virus from 2012 to 2016 and its serum antibody level among general healthy population during 2018–2020 in Jiangsu Province, China [PDF]
BMC Infectious DiseasesMumps is a vaccine-preventable disease with high contagious capability. Its incidence declined rapidly since one dose of mumps vaccine was introduced into Expanded Program of Immunization (EPI) in 2008 in China. Nonetheless, the outbreaks of mumps remain
Xiuying Deng +4 more
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The power of mumps virus: Matrix protein activates apoptotic pathways in human colorectal cell lines. [PDF]
PLoS ONE, 2023 New therapeutic approaches can significantly impact the control of colorectal cancer (CRC), which is increasing worldwide. In this study, we investigated the potential of targeting viral proteins to combat cancer cells.
Solmaz Morovati +4 more
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Repeated introductions and intensive community transmission fueled a mumps virus outbreak in Washington State [PDF]
eLife, 2021 In 2016/2017, Washington State experienced a mumps outbreak despite high childhood vaccination rates, with cases more frequently detected among school-aged children and members of the Marshallese community.
Louise H Moncla +9 more
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Exploration of microRNAs as transcriptional regulator in mumps virus infection through computational studies [PDF]
Scientific ReportsMumps is a common childhood infection caused by the mumps virus (MuV). Aseptic meningitis and encephalitis are usual symptoms of mumps together with orchitis and oophoritis that can arise in males and females, respectively.
Mubashir Hassan +4 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Introduction. Registration of regular epidemic outbreaks of mumps infection among young people, difficulties in the clinical diagnosis of the disease, the presence of specific clinical manifestations in adults with a severe course of infection make it ...
Vadislav V. Semerikov +5 more
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Seroprevalence of mumps in The Netherlands: dynamics over a decade with high vaccination coverage and recent outbreaks. [PDF]
PLoS ONE, 2013 Here we present mumps virus specific antibody levels in a large cross-sectional population-based serosurveillance study performed in the Netherlands in 2006/2007 (n = 7900).
Gaby Smits +8 more
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BMC Infectious Diseases, 2021 Background From October 2019–March 2020, several clusters of mumps cases were identified in the Netherlands. Our objective was to describe cluster-associated mumps virus transmission using epidemiological and molecular information in order to help future
Anita A. Shah +6 more
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Establishing a small animal model for evaluating protective immunity against mumps virus. [PDF]
PLoS ONE, 2017 Although mumps vaccines have been used for several decades, protective immune correlates have not been defined. Recently, mumps outbreaks have occurred in vaccinated populations.
Adrian Pickar +6 more
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Vaccines, 2022 Mumps outbreaks and breakthrough infections of measles and rubella have raised concerns about waning of vaccine-induced immunity after two doses of measles-mumps-rubella (MMR) vaccination.
Patricia Kaaijk +7 more
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