Combining genomics and epidemiology to track mumps virus transmission in the United States. [PDF]
PLoS Biology, 2020 Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks.
Shirlee Wohl +29 more
doaj +5 more sources
Repeated introductions and intensive community transmission fueled a mumps virus outbreak in Washington State [PDF]
eLife, 2021 In 2016/2017, Washington State experienced a mumps outbreak despite high childhood vaccination rates, with cases more frequently detected among school-aged children and members of the Marshallese community.
Louise H Moncla +9 more
doaj +3 more sources
Establishing a small animal model for evaluating protective immunity against mumps virus. [PDF]
PLoS ONE, 2017 Although mumps vaccines have been used for several decades, protective immune correlates have not been defined. Recently, mumps outbreaks have occurred in vaccinated populations.
Adrian Pickar +6 more
doaj +2 more sources
Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine. [PDF]
Int J Environ Res Public Health, 2020 Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps.
Su SB, Chang HL, Chen AK.
europepmc +2 more sources
Recombinant mumps virus as a cancer therapeutic agent
Molecular Therapy: Oncolytics, 2016 Mumps virus belongs to the family of Paramyxoviridae and has the potential to be an oncolytic agent. Mumps virus Urabe strain had been tested in the clinical setting as a treatment for human cancer four decades ago in Japan.
Arun Ammayappan +2 more
doaj +2 more sources
Structural basis for Glycan-receptor binding by mumps virus hemagglutinin-neuraminidase. [PDF]
Sci Rep, 2020 Mumps virus is one of the main cause of respiratory illnesses in humans, especially children. Among the viral surface glycoproteins, the hemagglutinin – neuraminidase, MuV-HN, plays key roles in virus entry into host cells and infectivity, thus ...
Forgione RE +8 more
europepmc +2 more sources
Genetic characteristic of mumps virus from 2012 to 2016 and its serum antibody level among general healthy population during 2018–2020 in Jiangsu Province, China [PDF]
BMC Infectious DiseasesMumps is a vaccine-preventable disease with high contagious capability. Its incidence declined rapidly since one dose of mumps vaccine was introduced into Expanded Program of Immunization (EPI) in 2008 in China. Nonetheless, the outbreaks of mumps remain
Xiuying Deng +4 more
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Easy and Rapid Detection of Mumps Virus by Live Fluorescent Visualization of Virus-Infected Cells. [PDF]
PLoS ONE, 2015 Mumps viruses show diverse cytopathic effects (CPEs) of infected cells and viral plaque formation (no CPE or no plaque formation in some cases) depending on the viral strain, highlighting the difficulty in mumps laboratory studies. In our previous study,
Tadanobu Takahashi +13 more
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Emergent lineages of mumps virus suggest the need for a polyvalent vaccine
International Journal of Infectious Diseases, 2018 Mumps outbreaks among vaccinated patients have become increasingly common in recent years. While there are multiple conditions driving this re-emergence, convention has suggested that these outbreaks are associated with waning immunity rather than ...
Meghan May +2 more
doaj +2 more sources
Exploration of microRNAs as transcriptional regulator in mumps virus infection through computational studies [PDF]
Scientific ReportsMumps is a common childhood infection caused by the mumps virus (MuV). Aseptic meningitis and encephalitis are usual symptoms of mumps together with orchitis and oophoritis that can arise in males and females, respectively.
Mubashir Hassan +4 more
doaj +2 more sources