A microbial muramidase improves growth performance and reduces inflammatory cell infiltration in the intestine of broilers chickens under Eimeria and Clostridium perfringens challenge [PDF]
: The objective of the present studies was to evaluate muramidase (MUR) supplementation in broilers under Eimeria and/or Clostridium perfringens challenge. For this, 2 experiments were conducted. Experiment 1.
Cristiano Bortoluzzi +7 more
doaj +3 more sources
Dietary muramidase leads to the downregulation of peptidoglycan biosynthesis and to caecal microbial modulation in laying hens [PDF]
Background In-feed muramidase enzyme has been linked to numerous advantages in several animal species. In the past years, muramidase has been shown to be effective in hydrolyzing peptidoglycan fragments, especially at small-intestine level in broilers ...
Salvatore Galgano +4 more
doaj +3 more sources
Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall [PDF]
Conjugative type 4 secretion systems (T4SSs) are the main driver for the spread of antibiotic resistance genes and virulence factors in bacteria.
Wei-Sheng Sun +4 more
doaj +4 more sources
Comparative effects of dietary muramidase and phytogenics on the growth performance and gastrointestinal functionality of broiler chickens [PDF]
: The objective of the present study was to compare the effectiveness of dietary supplementation of muramidase (MUR) and 2 phytogenic additives on the growth performance, intestinal morphology, bacteria load, and production of short-chain fatty acids ...
Necmettin Ceylan +3 more
doaj +3 more sources
Safety and efficacy of a feed additive consisting of muramidase produced with Trichoderma reesei DSM 32338 (Balancius™) for laying hens (DSM nutritional products) [PDF]
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of muramidase produced with Trichoderma reesei DSM 32338 (Balancius™) as a feed additive for laying hens.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
doaj +4 more sources
Dihydroartemisinin ameliorates innate inflammatory response induced by Streptococcus suis-derived muramidase-released protein via inactivation of TLR4-dependent NF-κB signaling [PDF]
Muramidase-released protein (MRP) is now being recognized as a critical indicator of the virulence and pathogenicity of Streptococcus suis (S. suis). However, the identification of viable therapeutics for S.
Yun Ji +3 more
doaj +3 more sources
A multi-omics approach to elucidate the mechanisms of action of a dietary muramidase administered to broiler chickens [PDF]
A novel dietary muramidase has been shown to have positive effects on broiler chickens. However, very little is known about its mechanisms of action. The present multi-omics investigation sought to address this knowledge gap.
Giorgio Brugaletta +9 more
doaj +2 more sources
Dietary muramidase improved growth performance, feed efficiency, breast meat yield, and welfare of turkeys from hatch to market [PDF]
: Muramidase is an enzyme that hydrolyzes peptidoglycans of bacterial cell walls and improves performance of broilers in a dose-dependent manner. An experiment was conducted to evaluate muramidase supplementation, at a high or step-down dose, in turkeys ...
C.L. Walk +5 more
doaj +2 more sources
Muramidase in Polycythemia Vera [PDF]
Abstract The serum muramidase levels of 45 patients with polycythemia vera were found to be significantly elevated above the values in 20 normal subjects. The patients with polycythemia vera who were studied included those with active disease, those controlled with myelosuppressive agents and those in the spent phase.
R A, Binder, H S, Gilbert
openaire +3 more sources
Effect of microbial muramidase supplementation in diets formulated with different fiber profiles for broiler chickens raised under various coccidiosis management programs [PDF]
: The objective of the present study was to determine the effects of muramidase (MUR) supplemented to diets formulated with different fiber sources (inert or fermentable) on the growth performance and intestinal parameters of broiler chickens raised ...
Cristiano Bortoluzzi +8 more
doaj +2 more sources

