Results 201 to 210 of about 10,350 (333)

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Exploring 2D Graphene‐Based Nanomaterials for Biomedical Applications: A Theoretical Modeling Perspective

Small Science, EarlyView.
Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos, Nevena Todorova, Irene Yarovsky   +2 more
wiley   +1 more source

Peptidoglycan editing by a specific ld-transpeptidase controls the muramidase-dependent secretion of typhoid toxin

Nature Microbiology, 2018
T. Geiger, M. Pazos, M. Lara-Tejero, W. Vollmer, J. Galán   +4 more
semanticscholar   +1 more source

First WGS Characterization of <i>Streptococcus suis</i> Isolated From a Case of Human Meningitis in Southern Italy. [PDF]

Transbound Emerg Dis
Fusco G, Dodaro S, Mauro MV, Greco F, Barca L, Paradiso R, Limone A, Garzi Cosentino M, Campione A, De Luca G, Cecere B, Greco S, Vangeli V, De Carlo E, Borriello G, Mastroianni A.   +15 more
europepmc   +1 more source

Beyond antibiotics: phage-encoded lysins against Gram-negative pathogens. [PDF]

Front Microbiol, 2023
Shah S, Das R, Chavan B, Bajpai U, Hanif S, Ahmed S.   +5 more
europepmc   +1 more source

Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability

Small Science, EarlyView.
Treponema pallidum protein Tp0136 enhances vascular permeability by upregulating CSRP1, which induces MYO10 exon 19 skipping, reducing MYO10 expression and triggering endothelial spheroidization. This study reveals a novel RNA splicing‐mediated dissemination mechanism, proposing CSRP1/MYO10 as therapeutic targets to limit bacterial dissemination in ...
Yu Lin, Xi Luo, Xu Shen, Xiao‐Lin Fu, Li‐Rong Lin, Tian‐Ci Yang   +5 more
wiley   +1 more source

Resuscitation-promoting factor (Rpf) terminates dormancy among diverse soil bacteria. [PDF]

mSystems
Lennon JT, Lehmkuhl BK, Chen L, Illingworth M, Kuo V, Muscarella ME.   +5 more
europepmc   +1 more source

Molecular typing of Streptococcus suis from pigs in Cuba

Biotecnología Aplicada
Streptococcus suis is a bacterium commonly carried by pigs in the respiratory tract; thus the infections caused by virulent strains are considered a problem in the swine industry.
Ivette Espinosa, Michel Báez, Belkis Corona, Daine Chong, Evelyn Lobo, Siomara Martínez   +5 more
doaj  

Fluorinated Zirconium‐Based Metal‐Organic Frameworks as Novel Sorbents to Improve the Efficacy of Hemodialysis Treatment

Small Science, EarlyView.
The incorporation of perfluoroalkyl chains into porous NU‐1000 leads to superior performance in the removal of uremic toxins from samples of CKD patients for two main reasons: improved stability and enhanced removal efficiency of protein‐bound toxins.
Fátima Guerrero, Francisco G. Moscoso, Joaquín Silvestre‐Albero, Alejandro Martin‐Malo, Carolina Carrillo‐Carrión   +4 more
wiley   +1 more source

New Bacteriophage <i>Pseudomonas</i> Phage Ka2 from a Tributary Stream of Lake Baikal. [PDF]

Viruses
Ilyina V, Gatina A, Trizna E, Siniagina M, Yadykova L, Ivannikova A, Ozhegov G, Zhuravleva D, Fedorova M, Gorshkova A, Evseev P, Drucker V, Bogachev M, Validov S, Kharitonova M, Kayumov A.   +15 more
europepmc   +1 more source