Results 201 to 210 of about 9,575 (303)

A novel peptidoglycan deacetylase modulates daughter cell separation in E. coli. [PDF]

PLoS Genet
Hernández-Rocamora VM, Martorana AM, Belloso A, Ballesteros D, Zaccaria M, Perez AJ, Iorga BI, Abia D, Gray J, Breukink E, Xiao J, Pazos M, Polissi A, Vollmer W.   +13 more
europepmc   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

Recombinant Extracellular Factor Protein of <i>Streptococcus suis</i> as Potential Candidate Protein for Antibodies Against <i>S. suis</i> Detection and Subunit Vaccine Development: <i>In Silico</i> and <i>In Vitro</i> Approaches. [PDF]

Vaccines (Basel)
Mitsuwan W, Saengsawang P, Boripun R, Rodríguez-Ortega MJ, Nwabor OF.   +4 more
europepmc   +1 more source

Muramidase (lysozyme) excretion in children. [PDF]

Archives of Disease in Childhood, 1969
T M, Barratt, R, Crawford
openaire   +2 more sources

Phycocyanobilin biosynthesis in Galdieria sulphuraria requires isomerization of phycoerythrobilin synthesized by bilin reductases

The FEBS Journal, EarlyView.
The biosynthesis of bilins, tetrapyrroles essential for light harvesting and sensing, is performed by specific enzymes (FDBRs). In Galdieria sulphuraria, both phycobiliprotein types bind phycocyanobilin, despite lacking the canonical synthesizing gene PCYA. Instead, PEBA and PEBB are encoded, producing phycoerythrobilin, proposed to be later isomerized
Federica Frascogna, Nathan C. Rockwell, Jana Hartmann, Julie M. Mudler, Nicole Frankenberg‐Dinkel   +4 more
wiley   +1 more source

New Perspectives in the Fight Against Multidrug-Resistant Bacteria: The Potential of Endolysin Biocomposites. [PDF]

Antibiotics (Basel)
Camacho-González CE, Cardona-Felix CS, Pérez-Larios A, Zamora-Gasga VM, Sáyago-Ayerdi SG, Sánchez-Burgos JA.   +5 more
europepmc   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

The FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal, Tomas Brom, Ivona Nečasová, Tomáš Janovič, Pavel Veverka, Naina Verma, Lukáš Uhrík, Lenka Hernychova, Ctirad Hofr   +8 more
wiley   +1 more source

A case of chronic myelomonocytic related lysozyme-induced nephropathy. [PDF]

BMC Nephrol
Kansal A, Peiris T, Ramnarain J, Wang J, Daneshvar S, Chow F, Fleming S.   +6 more
europepmc   +1 more source

Response to MEK inhibition with trametinib and tyrosine kinase inhibition with imatinib in multifocal histiocytic sarcoma. [PDF]

, 2017
Blum, S., Cairoli, A., de Leval, L., Homicsko, K., Michielin, O., Missiaglia, E., Naveiras, O., Voruz, S.   +7 more
core   +2 more sources

Serum Vitamin B12-Binding Capacity and Muramidase Changes With Cyclic Neutropenia Induced by Cytosine Arabinoside [PDF]

, 1971
Ralph Carmel, Charles A. Coltman
openalex   +1 more source