Results 31 to 40 of about 123,116 (255)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Indigenous house mice dominate small mammal communities in northern Afghan military bases

BMC Zoology, 2017
Background Small mammals are important reservoirs for pathogens in military conflicts and peacekeeping operations all over the world. This study investigates the rodent communities in three military bases in Northern Afghanistan.
Christoph Gertler, Mathias Schlegel, Miriam Linnenbrink, Rainer Hutterer, Patricia König, Bernhard Ehlers, Kerstin Fischer, René Ryll, Jens Lewitzki, Sabine Sauer, Kathrin Baumann, Angele Breithaupt, Michael Faulde, Jens P. Teifke, Diethard Tautz, Rainer G. Ulrich   +15 more
doaj   +1 more source

Functional signatures of evolutionarily young CTCF binding sites

BMC Biology, 2020
Background The introduction of novel CTCF binding sites in gene regulatory regions in the rodent lineage is partly the effect of transposable element expansion, particularly in the murine lineage.
Dhoyazan Azazi, Jonathan M. Mudge, Duncan T. Odom, Paul Flicek   +3 more
doaj   +1 more source

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

Advanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae‐In Ha, Eun‐Ju Hong, Sun‐Woo Lee, Jeongsook Kim, Doyeong Kim, Sang‐Min Park, Kyu Pil Lee, Hyo‐Jung Kwon, Jeong Hyun Kwon   +11 more
wiley   +1 more source

DOPAMAP, high-resolution images of dopamine 1 and 2 receptor expression in developing and adult mouse brains

Scientific Data, 2022
Measurement(s) mRNA expression Technology Type(s) transgenic Mouse • immunohistochemistry staining method Sample Characteristic - Organism Mus ...
I. E. Bjerke, E. R. Cullity, K. Kjelsberg, K. M. Charan, T. B. Leergaard, J. H. Kim   +5 more
doaj   +1 more source

Pathogen Detection in Ornithodoros sonrai Ticks and Invasive House Mice Mus musculus domesticus in Senegal

Microorganisms, 2022
Ornithodoros sonrai (O. sonrai) ticks are the only known vectors of Borrelia crocidurae, an agent of tick-borne relapsing fever (TBRF) borreliosis. Rodents serve as principal natural reservoirs for Borrelia.
Basma Ouarti, Moussa Sall, El Hadji Ibrahima Ndiaye, Georges Diatta, Adama Zan Diarra, Jean Michel Berenger, Cheikh Sokhna, Laurent Granjon, Jean Le Fur, Philippe Parola   +9 more
doaj   +1 more source

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Global climate change effect on Asian Mus musculus; Implication from last glacial maximum to the end of the 21st century

European Journal of Ecology
Global climate change poses unprecedented challenges to biodiversity, prompting urgent investigations into its effects on various species. This study focuses on Mus musculus, a small rodent species and a crucial indicator of ecosystem health.
Yaser Amir Afzali
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Intact, recombinant, and spliced forms of endogenous mouse mammary tumor viruses in inbred and wild mice

Journal of Virology
Endogenous retroviruses (ERVs) are chromosomally integrated viral copies that represent relics of past infections. Analysis of the sequenced genomes of 17 mouse strains, Mus musculus subspecies, and Mus spretus identified 29 ERVs of mouse mammary tumor ...
Oscar Lam, Esther Shaffer, Guney Boso, Christine A. Kozak   +3 more
doaj   +1 more source