Results 71 to 80 of about 17,657,887 (204)

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

Asian Journal of Andrology, 2015
Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus.
Kate L. Loveland, Andrew T. Major, Romaly Butler, Julia C. Young, David A. Jans, Yoichi Miyamoto   +5 more
doaj   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

Advanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam, JiWon Ahn, Jiwoo Shin, Nahong Lee, Youjin Lee, Sung min Cho, Paul Kim, Geonwoo Kang, Sang‐Jun Ha, Hyungil Jung   +9 more
wiley   +1 more source

Characteristics, Management, and Utilization of Muscles in Musculoskeletal Humanoids: Empirical Study on Kengoro and Musashi

Advanced Intelligent Systems, EarlyView.
Musculoskeletal humanoids exhibit rich biomechanical properties that remain insufficiently unified in prior discussions. This article systematically categorizes muscle characteristics into five properties: redundancy, independency, anisotropy, variable moment arm, and nonlinear elasticity, and analyzes their combined effects on control.
Kento Kawaharazuka, Kei Okada, Masayuki Inaba   +2 more
wiley   +1 more source

Additional file 1 of MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia

, 2023
Additional file 1: Table S2. Sequences of siRNA/miRNA. Table S3. Sequences of primers used for quantitative real-time PCR. Figure S1. Biological effects of miR-143 in AML. Figure S2. Overexpression of MiR-143 hardly unaffected the cell cycle, but suppressed cell migration in AML. Figure S3.
Li, Fanfan, Han, Yixiang, Chen, Rongrong, Jiang, Yinyan, Chen, Cheng, Wang, Xiaofang, Zhou, Jifan, Xu, Qingqing, Jiang, Songfu, Zhang, Si, Yu, Kang, Zhang, Shenghui   +11 more
openaire   +1 more source

Focused Ultrasound‐Induced Mechanical Ablation Affects the Carbohydrate Metabolism of Residual/Peri‐Focally Localized Glioblastoma Cells

International Journal of Cancer, EarlyView.
Glioblastoma (GBM) is highly aggressive and therapy‐resistant, warranting exploration of novel treatment strategies, among them mechanical high‐intensity focused ultrasound (mFUS), which holds significant promise for tumor ablation. The present study examined mFUS‐induced changes specifically in carbohydrate metabolism, which affects vulnerability to ...
Frieda Bayler, Jonna Holler, Jacqueline Clüver, Levi Johanning, Dana Hellmold, Nils Oliver Schröder, Jessica Nojszewski, Hajrullah Ahmeti, Carolin Kubelt‐Kwamin, Michael Synowitz, Janka Held‐Feindt   +10 more
wiley   +1 more source

Musashi. La leyenda del samurai [PDF]

, 2023
[ES] La editorial Quaterni presenta en el mercado hispanohablante el primero de los tres volúmenes en los que editará la obra más emblemática de Eiji Yoshikawa: Musashi. La leyenda del samurai.
Pereda González, Pablo
core   +1 more source

Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia

CNS Oncology, 2018
Aim: To investigate the time profile of hypoxia and stem cell markers in glioblastoma spheroids of known molecular subtype. Materials & methods: Patient-derived glioblastoma spheroids were cultured up to 7 days in either 2% or 21% oxygen.
Tine Rosenberg, Charlotte Aaberg-Jessen, Stine Asferg Petterson, Bjarne Winther Kristensen   +3 more
doaj   +1 more source

Molecular and clinical features of a Japanese medulloblastoma cohort: Subgroup‐specific prognostic stratification using economical/accessible diagnostic methods

Brain Pathology, EarlyView.
This study characterizes the molecular subgroup–specific features of a nationwide Japanese cohort comprising 242 medulloblastomas (MBs). Furthermore, we introduce SEE‐6‐CNA, a simple, cost‐effective, and FFPE‐compatible molecular test that is applicable to routine pathology samples and serves as a surrogate for risk stratification in non‐WNT/non‐SHH ...
Kohichi Go, Asako Katsuma, Ema Yoshioka, Tomoko Shofuda, Kohei Fukuoka, Koichi Ichimura, Yuko Matsushita, Yohei Mineharu, Yasuhide Makino, Takeshi Kawauchi, Atsushi Sasaki, Junko Hirato, Takeshi Inoue, Yoshinori Kodama, Masayuki Mano, Daisuke Kanematsu, Noriyuki Kijima, Naoki Kagawa, Dai Keino, Akitake Mukasa, Tomonari Suzuki, Koji Yoshimoto, Daisuke Kuga, Keishi Horiguchi, Shigeru Yamaguchi, Masayuki Kanamori, Kai Yamasaki, Kenichi Ishibashi, Takuya Akai, Masayoshi Yamaoka, Ryuji Ishizaki, Atsufumi Kawamura, Shigeo Ohba, Joji Ishida, Ryo Ando, Junya Fukai, Tomoru Miwa, Masazumi Fujii, Ai Muroi, Kuniaki Saito, Atsuko Harada, Yasuhiko Hayashi, Masahiro Nonaka, Young‐Soo Park, Yusuke Kobayashi, Tadashi Higuchi, Yosuke Miyairi, Kazuhisa Yoshifuji, Noriyoshi Takebe, Soichi Oya, Kosuke Nakajo, Mitsutoshi Nakada, Yoshiteru Nakano, Mizuki Kambara, Koji Adachi, Kazuhiro Tanaka, Hideo Nakamura, Yukihiko Sonoda, Ryuta Saito, Takafumi Wataya, Kazuhiko Kurozumi, Michael D. Taylor, Yoshitaka Narita, Soichiro Shibui, Hajime Arai, Hiroaki Sakamoto, Isao Date, Motoo Nagane, Ryo Nishikawa, Yoshiki Arakawa, Yonehiro Kanemura   +70 more
wiley   +1 more source

Indirect and Selective Patterning Strategy of Silver Nanowires Using Elastomer Poly(vinylidene Fluoride‐Co‐Hexafluoropropylene) for Stretchable Electronics

physica status solidi (a), Volume 223, Issue 12, 24 June 2026.
An indirect and selective patterning strategy is introduced to form embedded silver nanowire (AgNW) electrodes using the interfacial adhesion contrast between e‐PVDF‐HFP and PDMS. This method enables multiscale AgNW electrode patterning without masks or etching and improves mechanical and environmental stability.
Jinbo Shim, Jinsu Yoon, Hayun Kim, Yeeun Jeong, Hyukju Go, Yongtaek Hong   +5 more
wiley   +1 more source

Suppression of Musashi‑2 by the small compound largazole exerts inhibitory effects on malignant cells

International Journal of Oncology, 2020
RNA‑binding protein Musashi‑2 (MSI2) serves as a regulator of numerous pivotal biological processes associated with cancer initiation, development and resistance to treatment, and may represent a promising drug target. However, whether MSI2 inhibition is of value in antitumor treatment remains to be determined.
Min, Wang, Xiao-Yan, Sun, Yong-Chun, Zhou, Kuo-Jun, Zhang, Yong-Zhi, Lu, Jinsong, Liu, Yun-Chao, Huang, Gui-Zhen, Wang, Sheng, Jiang, Guang-Biao, Zhou   +9 more
openaire   +3 more sources