Results 61 to 70 of about 4,861 (176)

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state [PDF]

, 2014
The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but generally absent from differentiated cells, consistent with a role in cell state regulation.
Beard, Ber, Busch, Cancer Genome Atlas Network, Chakrabarti, Chigurupati, Colitti, Das, Dickson, dos Santos, Feng, Foubert, Han, Hirata, Imai, Ingolia, Jangi, Katz, Kawahara, Kayahara, Kharas, Kim, Knight, Lambert, Lee, Leong, Lobry, MacNicol, Mani, Mortazavi, Muto, Nakamura, Okabe, Okano, Okano, Park, Parker, Polyak, Ray, Reinke, Sakakibara, Sethi, Shapiro, Takahashi, Timmerman, Venables, Verhaak, Wang, Wang, Warzecha, Yamamoto, Yu, Zavadil   +52 more
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A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia

Nature Communications, 2020
Identifying leukaemia stem cells (LSC) and defining how they drive tumourigenesis might aid in the treatment of disease. Here, the authors show that a reporter Musashi 2 can serve as a platform to effectively identify leukemic stem cells and it is used ...
Kyle Spinler, Jeevisha Bajaj, Takahiro Ito, Bryan Zimdahl, Michael Hamilton, Armin Ahmadi, Claire S. Koechlein, Nikki Lytle, Hyog Young Kwon, Ferdous Anower-E-Khuda, Hao Sun, Allen Blevins, Joi Weeks, Marcie Kritzik, Jan Karlseder, Mark H. Ginsberg, Pyong Woo Park, Jeffrey D. Esko, Tannishtha Reya   +18 more
doaj   +1 more source

Musashi mediates translational repression of the Drosophila hypoxia inducible factor. [PDF]

, 2016
Adaptation to hypoxia depends on a conserved α/β heterodimeric transcription factor called Hypoxia Inducible Factor (HIF), whose α-subunit is regulated by oxygen through different concurrent mechanisms.
Acevedo, Julieta María, Bertolin, Agustina Paola, Blanco Obregón, Dalmiro Manuel, Gándara, Lautaro, Kanda, Hiroshi, Katz, Maximiliano Javier, Okano, Hideyuki, Pozzi, María Berta, Sorianello, Eleonora Mariana, Srebrow, Anabella, Wappner, Pablo, Yano, Masato   +11 more
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The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML [PDF]

, 2012
A unique characteristic of hematopoietic stem cells (HSCs) is the ability to self-renew. Several genes and signaling pathways control the fine balance between self-renewal and differentiation in HSCs and potentially also in leukemia stem cells. Recently,
Armstrong, Scott A., Arreba-Tutusaus, Patricia, Bullinger, Lars, Döhner, Konstanze, Fischer, Thomas, Gaebel, Julia, Heidel, Florian H., Hirt, Carsten, Lane, Steven W., Niederwieser, Dietger, Vasioukhin, Valera, Wang, Zhu   +11 more
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Integrating multiple molecular sources into a clinical risk prediction signature by extracting complementary information [PDF]

, 2016
Single nucleotide polymorphism (SNP) microarray data. SNP data underlying the finding in this article.
Axel Benner, Harald Binder, Lars Bullinger, Martin Schumacher, Richard F. Schlenl, Stefanie Hieke   +5 more
core   +7 more sources

NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1 [PDF]

, 2010
The balance between self-renewal and differentiation of neural progenitor cells is an absolute requirement for the correct formation of the nervous system.
Bailey, Timothy L., Barry, Guy, Boyle, Glen M., Gronostajski, Richard M., Hawkins, John, Lindwall, Charlotta, Little, Erica, Mason, Sharon, Moldrich, Randal X., Piper, Michael, Richards, Linda J., Sarkar, Anindita, Smith, Aaron G., Tole, Shubjha   +13 more
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Determinants of Academic Startups’ Orientation toward International Business Expansion

Administrative Sciences, 2016
This study explores the determinants of academic startups’ orientation toward international business expansion, focusing on their technological capabilities, availability of public support, the regional characteristics of their locations, and the ...
Shinya Suzuki, Hiroyuki Okamuro
doaj   +1 more source

The Contributions of Immigrants to Cancer Research in America [PDF]

, 2013
The report discusses the contributions of immigrant researchers and details the immigration difficulties experienced even by top cancer researchers. The study analyzed biographies of approximately 1,500 cancer researchers at the top cancer institutes. In
Stuart Anderson
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Effects of fermented wheat germ extract on oral cancer cells and research of biomarkers for diagnosis and prognosis of oral cancer [PDF]

, 2021
Oral squamous cell carcinoma (OSCC) represents one of the most aggressive types of cancer. The disease occurs when the accumulation of multiple genetic mutations in the oral epithelial cells leads to an irreversible damage of DNA and the cells lose ...
ZHURAKIVSKA, KHRYSTYNA
core   +1 more source

Specificity factors in cytoplasmic polyadenylation [PDF]

, 2013
Poly(A) tail elongation after export of an messenger RNA (mRNA) to the cytoplasm is called cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has roles in meiosis and development.
Afonina, Alarcon, Andres-Aguayo, Arumugam, Ascano, Aslam, Atkins, Atkins, Baines, Balagopal, Ballantyne, Bardwell, Barkoff, Barkoff, Barnard, Barnard, Bazzini, Belloc, Belloc, Benoit, Berger-Sweeney, Bermudez, Berndt, Bestman, Bestman, Bethune, Bilger, Bouvet, Bouvrette, Bouvrette, Brawerman, Brook, Brook, Burgess, Burgess, Burns, Burns, Bushell, Campbell, Campbell, Cao, Cao, Cao, Castagnetti, Cervello, Chan, Chang, Charlesworth, Charlesworth, Charlesworth, Charlesworth, Charlesworth, Chen, Chen, Chen, Cheng, Cheng, Chicoine, Choi, Clarke, Cogswell, Coll, Collier, Cooke, Costa, Craig, Darnell, Darnell, Dasgupta, De Moor, De Moor, Derry, Dettwiler, Di Giammartino, Dickson, Dickson, Didiot, Djuranovic, Du, Eckmann, Eckmann, Edwards, Eiring, Eliscovich, Ernoult-Lange, Ezeh, Fabian, Fan, Ferby, Fernandez-Miranda, Fox, Frank-Vaillant, Friend, Fu, Gavin, Gebauer, Gebauer, Gonzales, Gravina, Groisman, Groisman, Groisman, Groisman, Gunter, Guzeloglu-Kayisli, Guzeloglu-Kayisli, Hafer, Hake, Hake, Hodgman, Hoog, Hosoda, Hosoda, Houseley, Hu, Huang, Huang, Huang, Huarte, Hägele, Igea, Imai, Jenkins, Ji, Jin, Johnson, Jones, Juge, Kan, Kashiwabara, Kashiwabara, Kashiwabara, Katoh, Kaufmann, Kawahara, Keady, Keleman, Kerwitz, Kiessling, Kim, Kim, Kim, Kim, Kim, Kojima, Kolev, Kondrashov, Kosaka, Kraus, Kruttner, Kuehn, Kuehner, Kuhn, Kundel, Kuo, Kuo, Kwak, Kwak, Laishram, Laishram, Lee, Li, Lin, Lin, Luitjens, Lutz, Ma, Maisonneuve, Makeyev, Mandel, Martin, Martineau, Martinez, Martinson, Masuda, Maton, McEvoy, McGrew, McGrew, McPheeters, Meijer, Meijer, Meijer, Mellman, Mellman, Mendez, Mendez, Mendez, Menon, Millevoi, Moore, Moretti, Mukherjee, Nagaike, Nagaoka, Nairismagi, Nakahata, Nakahata, Nakahata, Nakanishi, Nakanishi, Nakel, Novoa, Okano, Oruganty-Das, Osborne, Ostareck-Lederer, Padmanabhan, Paffenholz, Paillard, Paillard, Papin, Paris, Paris, Pavlopoulos, Pederson, Peng, Piazzon, Pique, Preker, Proudfoot, Qu, Quenault, Racki, Radford, Rattenbacher, Reverte, Reverte, Reynolds, Roretz, Rouhana, Ryan, Rybarska, Sagata, Sagawa, Sakakibara, Sallés, Sasayama, Schmid, Schoenberg, Seli, Setoyama, Shcherbik, Sheets, Sheets, Shi, Shinojima, Si, Si, Si, Simon, Simon, Simon, Slevin, Soucek, Standart, Stebbins-Boaz, Suh, Suh, Suzuki, Takagaki, Takeda, Tan, Tay, Tay, Tay, Teplova, Theis, Tian, Todaro, Topalian, Tran, Tucker, Udagawa, van, Vardy, Vassalli, Vessey, Villalba, Vishnu, Vogler, Wang, Wang, Wang, Wang, Wang, Watanabe, Weill, Weiss, Wells, Wilt, Wiszniak, Wong, Wong, Wong, Wreden, Wu, Wu, Wu, Wu, Yang, Yang, Yang, Ye, Yen, Yeo, Zalfa, Zearfoss, Zeng, Zhao, Zhong, Zhuang   +311 more
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