Results 51 to 60 of about 2,758 (169)
Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms
Mushrooms have learned twice independently how to make the iconic magic mushroom natural product psilocybin. This article introduces the enzymes of the second pathway, found in a fiber cap mushroom. Curiously, the two pathways do not share any reaction, nor do the enzymes show a close relationship, but both pathways proceed via 4‐hydroxytryptamine as a
Tim Schäfer +3 more
wiley +1 more source
ABSTRACT Background The prevalence of cancer poses significant challenges to treatment, largely because of drug resistance along with other side effects. Current studies have been investigating the growth factors more than other biologic tumor features, such as neurobiologic features.
Mohammad Hossein Azadi +3 more
wiley +1 more source
Muscarinic receptor oligomerization [PDF]
G protein-coupled receptors (GPCRs) have been classically described as monomeric entities that function by binding in a 1:1 stoichiometric ratio to both ligand and downstream signalling proteins. However, in recent years, a growing number of studies has supported the hypothesis that these receptors can interact to form dimers and higher order oligomers
Marsango, Sara +3 more
openaire +2 more sources
Harnessing the potential of cells as complex biosensors promises the potential to create sensitive and selective detectors for discrimination of biodefense agents.
John Wikswo +6 more
doaj +1 more source
Neurochemical architecture of the central complex related to its function in the control of grasshopper acoustic communication. [PDF]
The central complex selects and coordinates the species- and situation-specific song production in acoustically communicating grasshoppers. Control of sound production is mediated by several neurotransmitters and modulators, their receptors and ...
Michael Kunst +3 more
doaj +1 more source
A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah +1 more
wiley +1 more source
Serotonin increases cilia-driven particle transport via an acetylcholine-independent pathway in the mouse trachea. [PDF]
BACKGROUND: Mucociliary clearance in the airways is driven by the coordinated beating of ciliated cells. Classical neuromediators such as noradrenalin and acetylcholine increase ciliary beat frequency and thus cilia-driven transport.
Peter König +3 more
doaj +1 more source
A novel synthetic approach for the preparation of [3H]muscimol (48.3 Ci/mmol, 1.8 TBq/mmol) based on the reduction of a suitably protected amide precursor using in situ generated tritioborane (BT3·THF) is reported. The method avoids the use of bulk tritiated water employed in established synthetic protocols and enables safe, reliable, and efficient ...
Michal Kriegelstein, Aleš Marek
wiley +1 more source
Aqueous semisynthesis of C-glycoside glycamines from agarose
Agarose was herein employed as starting material to produce primary, secondary and tertiary C-glycoside glycamines, including mono- and disaccharide structures.
Juliana C. Cunico Dallagnol +5 more
doaj +1 more source
Abstract Objective Investigate the tolerance, stability, and efficacy of topical 0.1% and 1% atropine in cats. Procedures Six cats underwent two trials separated by a 2‐week washout period. One drop of artificial tears was placed in one randomly selected eye (control), and one drop of either 0.1% atropine (Trial I) or 1% atropine (Trial II) was placed ...
Karin W. Handel +4 more
wiley +1 more source

