Results 81 to 90 of about 82,903 (289)

Intraoperative Bradycardia: Evaluating Vasovagal Events in Adult Suspension Microlaryngeal Surgery

open access: yesThe Laryngoscope, EarlyView.
This retrospective single‐surgeon cohort study of 190 adults undergoing suspension microlaryngoscopy found that 8.9% (17/190) developed significant intraoperative bradycardia consistent with a vasovagal response (VVR). No demographic, comorbidity, or procedural factors were significantly associated with VVR, though most affected patients required ...
Thomas Q. McClelland   +4 more
wiley   +1 more source

Cooperative Glutamatergic and Cholinergic Mechanisms Generate Short-Term Modifications of Synaptic Effectiveness in Prepositus Hypoglossi Neurons [PDF]

open access: yes, 2005
To maintain horizontal eye position on a visual target after a saccade, extraocular motoneurons need a persistent (tonic) neural activity, called "eye-position signal," generated by prepositus hypoglossi (PH) neurons.
Navarro Lopez, JDD   +2 more
core  

Direct in vitro and in vivo demonstration of muscarinic receptor binding by the novel radioligand, [3H]5-hydroxymethyltolterodine, in the bladder and other tissues of rats

open access: yesJournal of Pharmacological Sciences, 2020
In vitro and in vivo binding sites of [3H]-labeled 5-hydroxymethyltolterodine (5-HMT), a new radioligand for labeling muscarinic receptors in rat tissues were characterized.
Shizuo Yamada   +5 more
doaj   +1 more source

The Benefits of Adding Non‐Antimuscarinic Pharmaceuticals in Combination With Beta‐3 Agonists for Overactive Bladder Treatment: A Systematic Review

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith   +2 more
wiley   +1 more source

Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex

open access: yesFrontiers in Synaptic Neuroscience, 2015
Muscarinic cholinergic receptors modulate the activity and plasticity of the visual cortex. Muscarinic receptors are divided into 5 subtypes that are not homogeneously distributed throughout the cortical layers and cells types.
Marianne eGroleau   +3 more
doaj   +1 more source

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du   +8 more
wiley   +1 more source

ENANTIO- AND TISSUE-SETECTIVITY OF CHIRAL MUSCARINIC AGONISTS CARRYING A 1.3-OXATHIOLANE NUCLEUS

open access: yes, 1988
ln order to investigate tissue and enantioserectivity of 1,3-oxathiolane muscarinic agonists we have estimated potency, affinity and relative efficacy according to Furchgott and Bursztyn on isolated preparations of guinea pig ileum, atria and rat urinary
F. Gualtier   +3 more
core  

Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels [PDF]

open access: yes, 2005
The relationship between receptor-induced membrane phosphatidylinositol-4'5'-bisphosphate (PIP2) hydrolysis and M-current inhibition was assessed in single-dissociated rat sympathetic neurons by simultaneous or parallel recording of membrane current and ...
Abogadie, FC   +6 more
core  

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit   +5 more
wiley   +1 more source

Modulation of cholinergic synaptic transmission in an identified locust sensory pathway [PDF]

open access: yes, 2000
The monosynaptic connection between the locust forewing stretch receptor (fSR) and the first basalar motoneuron (BAl) is part of a sensory pathway involved in flight.
Judge, Sarah Jane
core  

Home - About - Disclaimer - Privacy