Results 101 to 110 of about 82,903 (289)
Environmental Toxicology, EarlyView.ABSTRACT Malathion (MAL) is a widely used organophosphate pesticide associated with hepatotoxicity through oxidative stress and apoptosis. Morin, a naturally occurring flavonoid, exhibits potent antioxidant and anti‐inflammatory properties. This study investigated oxidative stress, inflammatory, and apoptotic alterations induced by acute and subacute ...
Seval Yılmaz +3 more
wiley +1 more source
Once-daily glycopyrronium bromide, a long-acting muscarinic antagonist, for chronic obstructive pulmonary disease: a systematic review of clinical benefit [PDF]
, 2012 Charlotte Suppli UlrikDepartment of Pulmonary Medicine, Hvidovre Hospital and University of Copenhagen, Copenhagen, DenmarkBackground: Long-acting bronchodilators are central in the pharmacological management of patients with chronic obstructive ...
Ulrik CS, Ulrik, Charlotte Suppli
core +1 more source
Tuberculosis and Respiratory Diseases, 2019 Background Efficacy and safety of tiotropium bromide, a muscarinic receptor antagonist, in treatment of asthma have been reported. However, its effect on airway remodeling in chronic asthma of the elderly has not been clearly verified.
Ji Young Kang, M.D., Ph.D. +6 more
doaj
Possible involvement of acetylcholine-mediated inflammation in airway diseases
Allergology International, 2018 Inhaled bronchodilator treatment with a long acting muscarinic antagonist (LAMA) reduces symptoms and the risk of exacerbations in COPD and asthma. However, increasing evidence from cell culture and animal studies suggests that anti-muscarinic drugs ...
Akira Koarai, Masakazu Ichinose
doaj +1 more source
Integrative Zoology, EarlyView.A high‐quality chromosome‐level reference genome was constructed for Hucho bleekeri. Population structure and environmental adaptation of Hucho species were revealed by whole‐genome resequencing. ABSTRACT Salmonidae represents an important family in the study of genome evolution following genome duplication.
Yeyu Chen +9 more
wiley +1 more source
Constitutive activity of muscarinic acetylcholine receptors.
, 2006 We review the literature describing constitutive activity of the five muscarinic acetylcholine receptors in native and recombinant systems and discuss the effect of constitutive activity on muscarinic pharmacology in the context of modern models of ...
Spalding, Tracy, Burstein, Ethan
core +1 more source
6‐Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human
Andrology, EarlyView.ABSTRACT Background Epithelium‐derived catecholamines contribute to local regulation of genitourinary smooth muscle function, but the role of the endogenous 6‐nitrodopamine (6‐ND) in the prostate remains unknown. Objectives To determine whether 6‐ND is produced by mouse and human prostate and its role in smooth muscle regulation.
Alline Araujo Curiel +12 more
wiley +1 more source
Effect of aging on airway remodeling and muscarinic receptors in a murine acute asthma model
, 2013 Ji Young Kang, Sook Young Lee, Chin Kook Rhee, Seung Joon Kim, Soon Seog Kwon, Young Kyoon KimDepartment of Internal Medicine, College of Medicine, Catholic University of Korea, Seoul, KoreaBackground and objectives: The influence of aging on the ...
Lee SY +5 more
core
Expression of muscarinic receptor subtypes and M2-muscarinic inhibition of adenylyl cyclase in lung
, 1995 The relative distribution and absolute quantities of muscarinic receptor subtypes m1, m2, m3, and m4 were determined in membranes of canine trachealis muscle, bronchi, and lung parenchyma by immuno-precipitation with receptor subtype-specific rabbit ...
C. W. Emala +6 more
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