Results 281 to 290 of about 124,719 (350)

Role of muscarinic acetylcholine receptors on interleukin-2 formation in lymphocytes

, 2000
Yasunobu Okuma, Hiromichi Fujino, Toshihiko Murayama, Takashi Uehara, Yasuyuki Nomura   +4 more
openalex   +1 more source

Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor [PDF]

ACS Medicinal Chemistry Letters, 2017
openaire   +5 more sources

Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties

Neuropsychopharmacology, 2010
K. Leach, R. Loiacono, C. Felder, D. McKinzie, A. Mogg, David B. Shaw, P. Sexton, A. Christopoulos   +7 more
semanticscholar   +1 more source

Prejunctional muscarinic inhibitory control of acetylcholine release in the human isolated detrusor: involvement of the M₄ receptor subtype

, 2000
Gianluigi D’Agostino, María Laura Bolognesi, Adele Lucchelli, Davide Vicini, B. Balestra, Valeria Spelta, Carlo Melchiorre, Marcello Tonini   +7 more
openalex   +1 more source

Crystal structures of the M1 and M4 muscarinic acetylcholine receptors

Nature, 2016
D. Thal, Bingfa Sun, D. Feng, Vindhya Nawaratne, K. Leach, C. Felder, M. Bures, David A. Evans, W. Weis, P. Bachhawat, T. S. Kobilka, P. Sexton, B. Kobilka, A. Christopoulos   +13 more
semanticscholar   +1 more source

Multiple Topological Domains Mediate Subtype-specific Internalization of the M2 Muscarinic Acetylcholine Receptor

, 2000
Michael L. Schlador, Robert D. Grubbs, Neil M. Nathanson   +2 more
openalex   +1 more source

Effect of Intracavernous Simultaneous Injection of Acetylcholine and VIP on Canine Penile Erection [PDF]

, 1992
Aboseif, Sherif R., Bénard, Francois, Lue, Tom F., Stief, Christian Georg, Takahashi, Y., Tanagho, Emil A.   +5 more
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Muscarinic Acetylcholine Receptor Agonists as Novel Treatments for Schizophrenia.

American Journal of Psychiatry, 2022
Schizophrenia remains a challenging disease to treat effectively with current antipsychotic medications due to their limited efficacy across the entire spectrum of core symptoms as well as their often burdensome side-effect profiles and poor tolerability.
S. Paul, S. Yohn, M. Popiolek, Andrew C. Miller, C. Felder   +4 more
semanticscholar   +1 more source

Muscarinic acetylcholine receptor

Progress in Neurobiology, 1978
ABSTRACT Muscarinic acetylcholine receptors from rat cerebral cortex and small intestine were studied by the high affinity and high specific activity antagonists 3 H-3-quinuclidinyl benzilate (3-QNB) (29.4 Ci/mmol) and 3 H-N-methyl-4-piperidinyl benzilate (4-NMPB) (55.4 Ci/mmol).
Edith Heilbronn, Tamas Bartfai
openaire   +4 more sources

Muscarinic Acetylcholine Receptors

Current Pharmaceutical Design, 2006
Muscarinic acetylcholine receptors mediate diverse physiological functions. At present, five receptor subtypes (M(1) - M(5)) have been identified. The odd-numbered receptors (M(1), M(3), and M(5)) are preferentially coupled to G(q/11) and activate phospholipase C, which initiates the phosphatidylinositol trisphosphate cascade leading to intracellular ...
Masaru Ishii, Yoshihisa Kurachi
openaire   +2 more sources