Results 151 to 160 of about 34,397 (264)

Internalization of the m2 muscarinic acetylcholine receptor. Arrestin-independent and -dependent pathways.

The Journal of biological chemistry, 1997
Recent studies have identified agonist-dependent phosphorylation as a critical event in the rapid uncoupling of the m2 muscarinic cholinergic receptors (mAChR) from G-proteins and sequestration of the receptors away from the cell surface. However, mutant m2 mAChRs were identified that were phosphorylated but unable to desensitize in adenylyl cyclase ...
R, Pals-Rylaarsdam, V V, Gurevich, K B, Lee, J A, Ptasienski, J L, Benovic, M M, Hosey   +5 more
openaire   +1 more source

Activation of nematode G protein GOA‐1 by the human muscarinic acetylcholine receptor M2 subtype

The FEBS Journal, 2006
M. Minaba, S. Ichiyama, Katsura Kojima, M. Ozaki, Y. Kato   +4 more
semanticscholar   +1 more source

Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease

International Journal of COPD, 2018
Donald P Tashkin,1 Nicholas J Gross2 1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Department of Medicine, University Medical Research LLC, Saint Francis Hospital and Medical Center, Hartford, CT, USA Abstract:
Tashkin DP, Gross NJ
doaj  

ALLOSTERIC BINDING OF 9-METHOXY-ALPHA-LAPACHONE AND ALCURONIUM TO THE MUSCARINIC ACETYLCHOLINE RECEPTOR M2 SUBTYPE

, 1995
G. Dong, T. Haga, H. Itokawa, F. Mizobe
semanticscholar   +1 more source

Proteoliposome-based Selection of a Recombinant Antibody Fragment Against the Human M2 Muscarinic Acetylcholine Receptor

Monoclonal antibodies in immunodiagnosis and immunotherapy, 2014
Suharni, Y. Nomura, T. Arakawa, T. Hino, Hitomi Abe, Yoshiko Nakada-Nakura, Yumi Sato, H. Iwanari, M. Shiroishi, H. Asada, T. Shimamura, T. Murata, Takuya Kobayashi, T. Hamakubo, S. Iwata, N. Nomura   +15 more
semanticscholar   +1 more source

Dopamine and Acetylcholine in the Striatum: Circuit Interactions and Behavioral Control in Substance Use Disorders. [PDF]

Brain Sci
Dinckol O, Wenger NH, Copling A, Patel BP, Kutlu MG.   +4 more
europepmc   +1 more source

A complex interplay of various intracellular motifs determines G protein binding and activation of muscarinic receptors. [PDF]

Sci Rep
Kirchhofer SB, Jelinek V, Klingelhöfer K, Krett AL, Bünemann M.   +4 more
europepmc   +1 more source

Exploring the Evolving Role of Scopolamine in Pharmacotherapy: From Cognitive Impairment to Neuroplasticity?-A Narrative Review. [PDF]

Molecules
Kukla J, Olejnik P, Kasarełło K.
europepmc   +1 more source

Long-Acting Muscarinic Antagonists for the Treatment of Difficult-to-Treat and Severe Asthma: A Narrative Review Focusing on Inflammation from Bench to Bedside. [PDF]

J Inflamm Res
Calzetta L, Manzetti GM, Pistocchini E, Lauro RF, Gholamalishahi S, Cazzola M, Rogliani P.   +6 more
europepmc   +1 more source

mPFC Synaptosome Proteomics Reveals Novel Pathways and Muscarinic Receptor Changes in a Learned Helplessness Mouse Model. [PDF]

eNeuro
Abdulla ZI, Garcia-Milian R, Giahyue E, Fertuzinhos S, Collin F, Wang W, Lam TT, Nairn AC, Picciotto MR.   +8 more
europepmc   +1 more source