Results 131 to 140 of about 13,362 (255)

Effects of Nerve Growth Factor shRNA Inhibition on Asthma Phenotypes in a Mouse Model of Asthma

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2018
Nerve growth factor (NGF) plays an important role in airway hyper-responsiveness (AHR). In this study, we aimed at investigating the effect of NGF inhibition on AHR and other asthma phenotypes in a mouse model of asthma.
Jinhong Wu   +3 more
doaj  

Posttranslational modifications of human M3 muscarinic acetylcholine receptor: zooming in its functional implications

open access: yes, 2023
The human M3 muscarinic acetylcholine receptor (M3R) regulates many important physiological roles in the central and peripheral nervous systems, and it is involved in the pathophysiology of several neurodegenerative and autoimmune diseases, representing attractive potential pharmacological target for intervention.
openaire   +4 more sources

Random Mutagenesis of the M3 Muscarinic Acetylcholine Receptor Expressed in Yeast [PDF]

open access: hybrid, 2004
Bo Li   +6 more
openalex   +1 more source

Bis-Quinolinium Cyclophane Blockers of SK Potassium Channels Are Antagonists of M3 Muscarinic Acetylcholine Receptors [PDF]

open access: gold, 2020
Vladislav Bugay   +9 more
openalex   +1 more source

Pronounced Conformational Changes following Agonist Activation of the M3 Muscarinic Acetylcholine Receptor [PDF]

open access: hybrid, 2005
Sung‐Jun Han   +7 more
openalex   +1 more source

Identification and Structural Determination of the M3 Muscarinic Acetylcholine Receptor Basolateral Sorting Signal [PDF]

open access: hybrid, 2005
Heidi A. Iverson   +4 more
openalex   +1 more source

Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors. [PDF]

open access: yes, 2011
BACKGROUND: Enteric neurotransmitters that act at G protein-coupled receptors (GPCRs) are well known to acutely promote epithelial Cl(-) and fluid secretion.
Bertelsen, Lone S   +6 more
core   +1 more source

Regulation of Src family kinases by muscarinic acetylcholine receptors in heterologous cells and neurons

open access: yesFrontiers in Molecular Neuroscience
Five muscarinic acetylcholine (mACh) receptor subtypes are divided into two classes: the M1 class (M1, M3, and M5) and the M2 class (M2 and M4). The former is coupled to Gq proteins, while the latter is coupled to Gi/o proteins.
Li-Min Mao   +4 more
doaj   +1 more source

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