Results 131 to 140 of about 13,431 (223)
Integrating the inputs that shape pancreatic islet hormone release. [PDF]
The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
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Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the triterpenoid ...
Chisato Tanaka +12 more
doaj +1 more source
Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors. [PDF]
BACKGROUND: Enteric neurotransmitters that act at G protein-coupled receptors (GPCRs) are well known to acutely promote epithelial Cl(-) and fluid secretion.
Bertelsen, Lone S +6 more
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The relaxant effect of Ferula assafoetida on smooth muscles and the possible mechanisms [PDF]
Asafoetida (Ferula asafoetida) an oleo-gum-resin belongs to the Apiaceae family which obtained from the living underground rhizome or tap roots of the plant. F.
Boskabady, M.H., Khazdair, M.R.
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Muscarinic acetylcholine receptor M3 (CHRM3; HM3) [PDF]
openaire +1 more source
Muscarinic acetylcholine M receptors (mAChRs) belong to the G protein-coupled receptor (GPCR) superfamily and play a crucial role in regulating and controlling the release of acetylcholine (ACh). This review aims to focus on M3 receptor (M3R) subtype distribution, function, efficacy, and clinical applications.
Shi-wan-er Chen, Jie Wu
openaire +1 more source
Muscarinic acetylcholine receptor M3 (CHRM3; HM3) [PDF]
openaire +1 more source
Ligand-Induced Activation of the M3-Muscarinic Acetylcholine Receptor
This thesis explores the computer-aided drug design of the M3-muscarinic acetylcholine receptor in three chapters. The first chapter focuses on molecular docking to identify novel agonists using the ZINC12 library. A model of the M3 receptor was built based on the M2 receptor.
openaire +1 more source
Voiding Behavior and Efferent Bladder Function Altered in Mice Following Social Defeat but Not Witness Trauma [PDF]
Chess-Williams, Russ +3 more
core +1 more source
)Molecular mechanism of Sjogren’s syndrome : Immune response to M3R [PDF]
課題番号 ...
スミダ タカユキ, 住田 孝之
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