Results 181 to 190 of about 5,131 (212)

Characterization of Selective M5 Acetylcholine Muscarinic Receptor Modulators on Dopamine Signaling in the Striatum

The Journal of Pharmacology and Experimental Therapeutics, 2023
The type-5 muscarinic acetylcholine receptor (mAChR, M5) is almost exclusively expressed in dopamine (DA) neurons of the ventral tegmental area and substantia nigra pars compacta; therefore, they are ideally located to modulate DA signaling and underlying behaviors. However, the role of M5 in shaping DA release is still poorly characterized.
Vivien Zell, Greetje Teuns, Alexandra Stormy Needham, Sruti Mukherjee, Nathaniel Roscoe, Michelle Le, Lawrence Fourgeaud, Grace Woodruff, Anindya Bhattacharya, Mathieu Marella, Pascal Bonaventure, Wayne C. Drevets, Bartosz Balana   +12 more
openaire   +2 more sources

Muscarinic Acetylcholine Receptor M5

, 2020

openalex   +2 more sources

Estrogen prevents cerebrovascular deficits by the lack of M5 muscarinic acetylcholine receptor through MAPK activation

Neuroscience Research, 2007
Runa Araya, Naohito Kitamura, Tetsuya Kimura, Jürgen Wess, Masahisa Yamada   +4 more
openalex   +3 more sources

Muscarinic Acetylcholine Receptors Subtypes M1–M5 in the Somatic Muscles of Earthworm Lumbricus terrestris

Cell and Tissue Biology, 2022
Л. Ф. Нуруллин, Е. М. Волков   +1 more
openalex   +2 more sources

Role for M₅ muscarinic acetylcholine receptors in cocaine addiction

Journal of Neuroscience Research, 2003
AbstractMuscarinic cholinergic receptors of the M5 subtype are expressed by dopamine‐containing neurons of the ventral tegmentum. These M5 receptors modulate the activity of midbrain dopaminergic neurons, which play an important role in mediating reinforcing properties of abused psychostimulants like cocaine.
Fink-Jensen, A., Fedorova, I., Wörtwein, Gitta, Woldbye, David P. D., Rasmussen, T., Thomsen, M., Bolwig, Tom G., Knitowski, K.M., McKinzie, D.L., Yamada, M., Wess, J., Basile, A.   +11 more
openaire   +3 more sources

The Muscarinic Acetylcholine Receptor M₅: Therapeutic Implications and Allosteric Modulation

ACS Chemical Neuroscience, 2018
The muscarinic acetylcholine receptor (mAChR) subtype 5 (M5) was the most recent mAChR to be cloned and has since emerged as a potential therapeutic target for a number of indications. Early studies with knockout animals have provided clues to the receptor's role in physiological processes related to Alzheimer's disease, schizophrenia, and addiction ...
Craig W. Lindsley, Craig W. Lindsley, Aaron T. Garrison, Aaron T. Garrison, Aaron M. Bender, Aaron M. Bender   +5 more
openaire   +3 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Victoria Metaxa   +2 more
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

Breast Cancer Statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Hyuna Sung, Kimberly D Miller, Rebecca L Siegel   +2 more
exaly