M3 Muscarinic Receptor Antagonists Inhibit Small Cell Lung Carcinoma Growth and Mitogen-Activated Protein Kinase Phosphorylation Induced by Acetylcholine Secretion [PDF]
Pingfang Song+8 more
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Abstract Aims Inconsistent associations have been reported between steatotic liver disease (SLD) and depression. We aimed to investigate the cross‐sectional and prospective associations between MRI‐derived liver fat, SLD and depression. Materials and Methods We used UK Biobank data. Liver fat was measured with liver MRI proton density fat fraction. SLD
Qi Feng+3 more
wiley +1 more source
Nα-nitro L-arginine methylester and other alkyl esters of L-arginine are muscarinic antagonists
Dennis J. Cheek+3 more
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Sleep-Predominant Lowering of Ambulatory Blood Pressure by Bedtime Inhalation of a Novel Muscarinic M3 Receptor Antagonist: A New “Bronchoantihypertensive” Strategy Targeting the Lung in Hypertension with Chronic Obstructive Pulmonary Disease [PDF]
Kazuomi Kario+2 more
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This systematic review and meta‐analysis evaluates the impact of SGLT‐2 inhibitors on COPD exacerbations in patients with Type 2 diabetes mellitus (T2DM). Our findings demonstrate that SGLT‐2 inhibitors significantly reduce the frequency of COPD exacerbations by 35% compared to other antidiabetic agents, offering dual benefits in glycemic control and ...
Muhammed Shabil+14 more
wiley +1 more source
Alterations in histamine responses between juvenile and adult urinary bladder urothelium, lamina propria and detrusor tissues [PDF]
Chess-Williams, Russ+2 more
core +1 more source
A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 Antagonist Reduces Seizures without Impairing Hippocampus-Dependent Learning [PDF]
Douglas J. Sheffler+14 more
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Abstract The role of excessive airway constriction in the hyperresponsiveness to nebulized methacholine in mice with experimental asthma is still contentious. Yet, there have been very few studies investigating whether the increased in vivo response to methacholine caused by experimental asthma is associated with a corresponding increase in ex vivo ...
Andrés Rojas‐Ruiz+7 more
wiley +1 more source
inhibitor 2-[(4-methylphenyl)sulfonylcarbamido]-1-(4-nitrobenzyl)pyridinium bromide (2-AP27) is a muscarinic M2 receptor antagonist [PDF]
Vytenis Arvydas Skeberdis+4 more
openalex +1 more source