EEG Time-Frequency Clustering Reveals Spectral Signatures of Glutamatergic and Cholinergic Activities and Their Interrelations. [PDF]
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Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways. [PDF]
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Muscarinic Antagonist Antidepressants Lacking Cognitive Deficits
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Risk of Hospitalized Cardiovascular Events Associated with LAMA/LABA/ICS FDC versus LABA/ICS FDC in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Cohort Study. [PDF]
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Xanomeline-Trospium Chloride as a New Paradigm in the Treatment of Schizophrenia Through Muscarinic Modulation: A Renewed Hope in Psychiatric Care. [PDF]
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Ten Years in a Pediatric Center: Detecting Esophageal Pathology and Symptoms in Aerodigestive Patients. [PDF]
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Long-acting muscarinic antagonists
Expert Review of Clinical Pharmacology, 2015Chronic obstructive pulmonary disease (COPD) is a major cause of death and disability worldwide. Inhaled bronchodilators are the mainstay of COPD pharmacological treatment. Long-acting muscarinic antagonists (LAMAs) are a major class of inhaled bronchodilators.
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Muscarinic Receptor Antagonists.
Handbook of Experimental Pharmacology, 2016Parasympathetic activity is increased in patients with chronic obstructive pulmonary disease (COPD) and asthma and appears to be the major reversible component of airway obstruction. Therefore, treatment with muscarinic receptor antagonists is an effective bronchodilator therapy in COPD and also in asthmatic patients.
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