Results 211 to 220 of about 43,320 (312)

Residual Effects of Acute and Subchronic Zolpidem Treatments on Attentional Processes in Aged Female Rats

open access: yesFundamental &Clinical Pharmacology, Volume 40, Issue 1, January 2026.
ABSTRACT Rational Zolpidem, a hypnotic Z‐drug commonly prescribed to promote sleep, is predominantly used over the age of 50. In this elderly population, adverse behavioral disturbances, impaired driving performance, and an increased risk of falls have been frequently reported.
Marianne Leger   +7 more
wiley   +1 more source

Combined treatment with a β3‐adrenergic receptor agonist and a muscarinic receptor antagonist inhibits detrusor overactivity induced by cold stress in spontaneously hypertensive rats [PDF]

open access: bronze, 2016
Tetsuya Imamura   +8 more
openalex   +1 more source

Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal   +3 more
wiley   +1 more source

Muscarinic antagonist effects on experimental chick myopia

open access: yesExperimental Eye Research, 1991
R A, Stone, T, Lin, A M, Laties
openaire   +2 more sources

Sevoflurane Inhibits Layer 5 Pyramidal Neurons via Kv1.2‐Dependent Modulation of Subthreshold Currents

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
General anesthetics suppress cortical activity, but their cellular mechanisms remain unclear. We investigated how the volatile anesthetic sevoflurane affects layer 5 pyramidal neurons in the auditory cortex. Using patch‐clamp recordings and computational modeling, we found that low‐dose sevoflurane reduces neuronal firing through Kv1.2 channel ...
Aelton S. Araujo   +4 more
wiley   +1 more source

Synthesis and evaluation of 4,6-disubstituted pyrimidines as CNS penetrant pan-muscarinic antagonists with a novel chemotype. [PDF]

open access: yesBioorg Med Chem Lett, 2017
Bender AM   +8 more
europepmc   +1 more source

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