Results 191 to 200 of about 25,052 (251)

The risk factors of future exacerbations and treatment responses among different inhalation therapies of patients with preserved ratio impaired spirometry. [PDF]

J Glob Health
Cao J, Sun T, Yang H, Zhou L, Shen Q, Lin L, Li T, Zhang P, Zeng Y, Chen P, Song Q, Lei S, Li J.   +12 more
europepmc   +1 more source

A pragmatic, multicentre, placebo-controlled, 3-arm, double-blinded, randomised controlled trial, incorporating an internal pilot, to determine the role of bronchodilators in preventing exacerbations of bronchiectasis.

Health Technol Assess
Wilson N, Morton M, Homer T, Breeze Konkoth A, Joyce R, Kershaw A, Wilde H, Liddle A, Wason J, Ternent L, Allen M, Lord R, Steer J, Devereux G, Chalmers JD, Hill AT, Haworth CS, Hurst JR, De Soyza AA.   +18 more
europepmc   +1 more source

Characterization of Patients with COPD and GOLD E Classification in the United States. [PDF]

Int J Chron Obstruct Pulmon Dis
Bhatt SP, Zhang Y, White J, Stanford RH, Mayen Herrera E, Cunoosamy D, Djandji M, Soliman M, Qureshi T, Subramaniam A.   +9 more
europepmc   +1 more source

The effects of acute and repeated M1 agonist VU0364572 administration on cocaine-vs-food choice in male and female Sprague-Dawley rats. [PDF]

Drug Alcohol Depend
Marsh SA, Banks ML.
europepmc   +1 more source

Mechanisms of Pilocarpine-Induced Nitric Oxide and Prostaglandin Production in Porcine Ciliary Muscle. [PDF]

FASEB Bioadv
Benozzi G, Quinteros Villarruel E, Zuluaga AF, Orman B.   +3 more
europepmc   +1 more source

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Long-acting muscarinic antagonists

Expert Review of Clinical Pharmacology, 2015
Chronic obstructive pulmonary disease (COPD) is a major cause of death and disability worldwide. Inhaled bronchodilators are the mainstay of COPD pharmacological treatment. Long-acting muscarinic antagonists (LAMAs) are a major class of inhaled bronchodilators.
Andrea S Melani
exaly   +3 more sources

Role of muscarinic antagonists in asthma therapy

Expert Review of Respiratory Medicine, 2017
Higher parasympathetic tone has been reported in asthmatics. In general, cholinergic contractile tone is increased by airway inflammation associated with asthma. Nevertheless, the role of muscarinic antagonists for the treatment of asthma has not yet been clearly defined.
Mario Cazzola, Josuél Ora, Paola Rogliani   +2 more
exaly   +6 more sources

The interaction of selective and non-selective antagonists with pre- and postjunctional muscarinic receptor subtypes in the guinea pig trachea

European Journal of Pharmacology, 1993
Muscarinic receptor antagonists were used to study prejunctional M2 and postjunctional M3 receptors in the isolated guinea pig trachea. The effects of four M2-selective muscarinic receptor antagonists (gallamine, methoctramine, AQ-RA 741 and AF-DX 116 ...
Ad F Roffel, Johan Zaagsma
exaly   +2 more sources

Muscarinic Receptor Antagonists

2016
Parasympathetic activity is increased in patients with chronic obstructive pulmonary disease (COPD) and asthma and appears to be the major reversible component of airway obstruction. Therefore, treatment with muscarinic receptor antagonists is an effective bronchodilator therapy in COPD and also in asthmatic patients.
Maria Gabriella, Matera, Mario, Cazzola
openaire   +2 more sources

Selective Muscarinic Receptor Agonists and Antagonists

Pharmacology & Toxicology, 1996
Abstract:Muscarinic receptors are composed of a family of four subtypes each of which can be distinguished pharmacologically and structurally. The physiological role of each subtype in the central and peripheral nervous systems remains to be clarified, due, in part, to a lack of agonists and antagonists with adequate subtype selectivity.
R M, Eglen, N, Watson
openaire   +2 more sources