The Cholinergic Pathways in Inflammation: A Potential Pharmacotherapeutic Target for COPD
Frontiers in Pharmacology, 2018 In COPD, the activity of the cholinergic system is increased, which is one of the reasons for the airflow limitation caused by the contraction of airway smooth muscles.
Mitsuhiro Yamada, Masakazu Ichinose
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Projections of Healthcare Resource Utilization and Costs Related to Exacerbations for Budesonide/Glycopyrrolate/Formoterol Fumarate Versus Dual Long-Acting Muscarinic Antagonist/Long-Acting β 2 -Agonist and Inhaled Corticosteroid/Long-Acting β 2 -Agonist Therapies in Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease [PDF]
, 2021 Enrico De Nigris +5 more
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Epilepsia Open, EarlyView.Abstract Objective Variants in KCNQ2 encoding the voltage‐gated potassium channel KV7.2 are associated with developmental and epileptic encephalopathy (DEE) of varying severity. This study examined the relationship of KCNQ2 variant dysfunction with the neurodevelopmental phenotype of individuals with KCNQ2‐DEE. Methods A parent‐reported survey gathered
Jessa S. Bidwell +4 more
wiley +1 more source
Clinical potential of aclidinium bromide in chronic obstructive pulmonary disease
Therapeutics and Clinical Risk Management, 2014 Jun Zhong, Michael Roth Pneumology and Pulmonary Cell Research, Department of Biomedicine and Internal Medicine, University Hospital Basel, Basel, Switzerland Abstract: Chronic obstructive pulmonary disease (COPD) is increasing worldwide and is ...
Zhong J, Roth M
doaj
Executive summary: Japanese guidelines for adult asthma (JGL) 2021
Allergology International, 2023 Asthma is characterized by chronic airway inflammation, variable airway narrowing, and sensory nerve irritation, which manifest as wheezing, dyspnea, chest tightness, and cough.
Akio Niimi +8 more
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New strategic insights into managing fungal biofilms [PDF]
, 2015 Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
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Food Frontiers, EarlyView.This study highlights the memory‐enhancing effects of walnuts, almonds, and Torreya, with walnuts showing the strongest potential to improve cognitive function and delay brain aging. ABSTRACT This study explored the memory‐enhancing potential of seven commercially available nuts through nutritional profiling, metabolomics, network pharmacology, and ...
Jiamin Chen +10 more
wiley +1 more source
Journal of Pharmacological Sciences, 2010 Overactive bladder (OAB) syndrome is a common condition that is most often observed in the elderly. Pharmacological treatment with muscarinic receptor antagonists has been most widely used for OAB. An antimuscarinic agent, solifenacin, showed the highest
Akiyoshi Ohtake +3 more
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Long-Term Efficacy of Mirabegron Add-On Therapy to Antimuscarinic Agents in Patients With Spinal Cord Injury [PDF]
Annals of Rehabilitation Medicine, 2019 Objective To evaluate the long-term efficacy of mirabegron add-on therapy in patients with spinal cord injury (SCI) based on an urodynamic study.
Seok-Hee Han +4 more
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Molecular imprinting for neurology: Materials, applications, and limitations
Ibrain, EarlyView.Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma +3 more
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