Results 61 to 70 of about 18,712 (165)
Allergy, EarlyView.Screening of 250 natural products identified ginsenoside Rb1 (gRb1) as a potent modulator of regulatory T cells (Tregs) and inflammatory T cells. gRb1 increased IL‐10‐ and TGF‐β‐expressing Tregs while reducing Th17, Th1, and Th2 populations in both asthma model mice and human PBMCs.
Susanna Choi +14 more
wiley +1 more source
LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD : a systematic review and meta-analysis [PDF]
, 2017 Acknowledgments The meta-analysis work was performed by Guruprasad Rao KS and Sharanbasappa Durg of Molecular Connections (P) Ltd, Bangalore, India, under the guidance of the manuscript authors and Novartis Pharma AG (Basel, Switzerland). Medical writing
Altman, Pablo +8 more
core +2 more sources
Muscarinic Receptor Antagonists: Effects on Pulmonary Function [PDF]
, 2011 In healthy lungs, muscarinic receptors control smooth muscle tone, mucus secretion, vasodilation, and inflammation. In chronic obstructive pulmonary disease (COPD) and asthma, cholinergic mechanisms contribute to increased bronchoconstriction and mucus secretion that limit airflow.
Allison D. Fryer, Kalmia S. Buels
openaire +3 more sources
Economic Impact of Allergic Diseases and Asthma—The HEAD Pan‐European Registry
Allergy, EarlyView.This registry‐based study demonstrates the substantial economic burden of allergic diseases across Europe with a high degree of heterogeneity between countries. Treatments and specialist visits are the primary drivers of healthcare costs. Asthma poses the highest disease burden.
Ioana Agache +66 more
wiley +1 more source
New strategic insights into managing fungal biofilms [PDF]
, 2015 Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
core +3 more sources
Allergy, EarlyView.This study investigates longitudinal effects of dupilumab on the nasal passage and gastrointestinal microbiota in patients with diffuse type 2 CRSwNP. CRSwNP patients show altered nasal microbiota composition compared to healthy individuals. Dupilumab treatment is associated with a shift of nasal microbiota in CRSwNP, with increasing beneficial genera (
Fabio S. Ryser +9 more
wiley +1 more source
Muscarinic receptor oligomerization [PDF]
, 2018 G protein-coupled receptors (GPCRs) have been classically described as monomeric entities that function by binding in a 1:1 stoichiometric ratio to both ligand and downstream signalling proteins.
Alvarez-Curto, Elisa +3 more
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract To determine the effectiveness of various interventions in reducing myopia progression in children. Literature databases were searched on December 2, 2023: PubMed, Embase, the Cochrane Central, Web of Science Core Collection, BIOSIS Previews, Current Contents Connect, Data Citation Index, Derwent Innovations Index, KCI‐Korean Journal Database,
Diana Chabané Schmidt +9 more
wiley +1 more source
Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power
Acta Ophthalmologica, EarlyView.Abstract Purpose The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.
Seyed Mohsen Ebrahimi +8 more
wiley +1 more source
Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma. [PDF]
, 2015 BACKGROUND: Despite the availability of several evidence-based therapies and non-pharmacological strategies to improve control of symptoms and prevent exacerbations of asthma, patients with asthma continue to be at risk for mortality and morbidity ...
Allison +23 more
core +2 more sources