Results 91 to 100 of about 1,290,722 (202)

Muscarinic Receptor PET in Neurodegeneration: Promise, Pitfalls, and Translational Priorities. [PDF]

Med Sci (Basel)
Filippi L, Danieli R.
europepmc   +1 more source

Role of Muscarinic Receptor Signaling Processes in Specific Aspects of Morphine-Induced Respiratory Depression in Rats. [PDF]

Pharmaceuticals (Basel)
Getsy PM, May WJ, Baby SM, Coffee GA, Qiu Y, Cheng F, Bates JN, Lewis SJ.   +7 more
europepmc   +1 more source

Gut microbial trimethylamine N-oxide generation promotes risk of atrial fibrillation via muscarinic receptor-mediated autonomic dysfunction. [PDF]

J Clin Invest
Arjunan S, Pemberton I, Li XS, Sangwan N, Akino L, Opoku E, Verbovetskiy D, Nemet I, Kim HS, Masumiya H, Wang Z, Lupica JA, Tian MY, Mao K, Mallela DP, Mohan ML, Schumacher SM, Rennison JH, Prasad SVN, Laurita KR, Chodisetty V, Chung MK, Van Wagoner DR, Barnard J, Smith JD, Wazni O, Hazen SL, Koeth RA.   +27 more
europepmc   +1 more source

Physiological functions of muscarinic receptor M3

Muscarinic receptors belong to the family of G-protein coupled receptors. G-proteins are heterotrimeric GTP-binding proteins that transfer signals from receptors to effectors. Effectors change levels of second messengers in the cell.
Urbánková, Anna
core  

mPFC Synaptosome Proteomics Reveals Novel Pathways and Muscarinic Receptor Changes in a Learned Helplessness Mouse Model. [PDF]

eNeuro
Abdulla ZI, Garcia-Milian R, Giahyue E, Fertuzinhos S, Collin F, Wang W, Lam TT, Nairn AC, Picciotto MR.   +8 more
europepmc   +1 more source

Efficacy and safety of the muscarinic receptor agonist KarXT (Xanomeline-Trospium) in schizophrenia: a systematic review, meta-analysis and Bayesian sensitivity analysis. [PDF]

Int J Neuropsychopharmacol
Sharma N, Khatib MN, R R, Kaur M, Srivastava M, Barwal A, Prasad GVS, Rajput P, Mittal V, Shabil M, Kumar A, Bushi G, Mehta R, Satapathy P, Sah S.   +14 more
europepmc   +1 more source

Activating Muscarinic Receptor Signaling in Intrapancreatic Neurons Is Required for Parasympathetic Cholinergic Control of Pancreatic Cell Function. [PDF]

Diabetes
Levi NJ, Tamayo Garcia A, Sokolov M, Barro-Soria R, Caicedo A.   +4 more
europepmc   +1 more source

Regulation of muscarinic receptor-mediated sAPP release

, 2003
The amyloid precursor protein (APP) is a transmembrane protein that produces βA4 amyloid peptide, found in the brains of Alzheimer's disease (AD), by proteolytic cleavage.
김진형
core  

Dualsteric Agonist for M2 Muscarinic Receptor Causes Oxidative Stress and Mitochondrial Alteration in Human Glioblastoma Cancer Stem Cells. [PDF]

J Neurochem
Guerriero C, De Nuccio C, Petrone M, Rinaldi T, Cirigliano A, Visentin S, Bernardo A, Conti L, Matera C, De Amici M, Dallanoce C, Tata AM.   +11 more
europepmc   +1 more source

Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics. [PDF]

Elife, 2023
Vuckovic Z, Wang J, Pham V, Mobbs JI, Belousoff MJ, Bhattarai A, Burger WAC, Thompson G, Yeasmin M, Nawaratne V, Leach K, van der Westhuizen ET, Khajehali E, Liang YL, Glukhova A, Wootten D, Lindsley CW, Tobin A, Sexton P, Danev R, Valant C, Miao Y, Christopoulos A, Thal DM.   +23 more
europepmc   +1 more source