Results 121 to 130 of about 55,054 (301)

Methacholine hyperresponsiveness in mice with house dust mite‐induced lung inflammation is not associated with excessive airway constriction ex vivo

open access: yesExperimental Physiology, EarlyView.
Abstract The role of excessive airway constriction in the hyperresponsiveness to nebulized methacholine in mice with experimental asthma is still contentious. Yet, there have been very few studies investigating whether the increased in vivo response to methacholine caused by experimental asthma is associated with a corresponding increase in ex vivo ...
Andrés Rojas‐Ruiz   +7 more
wiley   +1 more source

Intracellular calcium release mediated by two muscarinic receptor subtypes [PDF]

open access: bronze, 1988
Erwin Neher   +4 more
openalex   +1 more source

Endothelial TRPV4–Cx43 signalling complex regulates vasomotor tone in resistance arteries

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we investigate, for the first time, the role of endothelial Cx43 hemichannels (hCx43) in the regulation of vasomotor tone. We discovered that TRPV4 channels and Cx43 are in proximity within the endothelium of mouse arterioles.
Pía C. Burboa   +7 more
wiley   +1 more source

Phospholipase C Involvement in Activation of the Muscarinic Receptor-Operated Cationic Current in Guinea Pig Ileal Smooth Muscle Cells

open access: yesJournal of Pharmacological Sciences, 2004
In guinea pig single ileal smooth muscle cells held under voltage-clamp, the role of phospholipase C (PLC) in activation of the muscarinic receptor-operated cationic current (Icat) was studied. U73122, a PLC inhibitor, prevented the generation of Icat by
Hiroyuki Okamoto   +7 more
doaj  

Muscarinic receptor antagonists and airway inflammation: A systematic review on pharmacological models. [PDF]

open access: yesHeliyon, 2022
Calzetta L   +5 more
europepmc   +1 more source

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