Results 131 to 140 of about 55,054 (301)

Neuron‐Derived Extracellular Vesicles: Emerging Biomarkers and Functional Mediators in Alzheimer's Disease, With Comparative Insights Into Neurodevelopment and Aging

Developmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurodegenerative disorders characterized by the accumulation of amyloid‐β (Aβ) peptide and phosphorylated tau protein in the brain. Despite intensive efforts, early diagnosis and monitoring of AD remain challenging due to the lack of reliable biomarkers that can detect the disease in its ...
Ceren Perihan Gonul, Bilge Karacicek, Sermin Genc   +2 more
wiley   +1 more source

The Forefront for Novel Therapeutic Agents Based on the Pathophysiology of Lower Urinary Tract Dysfunction: Bladder Selectivity Based on In Vivo Drug–Receptor Binding Characteristics of Antimuscarinic Agents for Treatment of Overactive Bladder

Journal of Pharmacological Sciences, 2010
We have reviewed the binding of antimuscarinic agents, used to treat urinary dysfunction in patients with overactive bladder, to muscarinic receptors in target and non-target tissues in vivo.
Akira Yoshida, Tomomi Fujino, Shuji Maruyama, Yoshihiko Ito, Yuko Taki, Shizuo Yamada   +5 more
doaj  

Astrocytes Reduce Store-Operated Ca²⁺ Entry in Microglia under the Conditions of an Inflammatory Stimulus and Muscarinic Receptor Blockade. [PDF]

Pharmaceuticals (Basel), 2022
Kim YJ, Shin YK, Seo E, Seol GH.
europepmc   +1 more source

Muscarinic Cholinergic Receptors in Mammalian Brain: Differences Between Bindings of Acetylcholine and Atropine

, 1978
Shuji Uchida, Kunio Takeyasu, Seiji Ichida, Hiroshi Yoshida   +3 more
openalex   +1 more source

Postganglionic muscarinic inhibitory receptors in pulmonary parasympathetic nerves in the guinea‐pig [PDF]

, 1986
David Faulkner, A.D. Fryer, Jennifer Maclagan   +2 more
openalex   +1 more source

Combined Effects of Intermittent Hypoxia and Amyloid Beta on Hippocampal Activity, Its Cholinergic Modulation, and Memory

Hippocampus, Volume 35, Issue 4, July 2025.
ABSTRACT Obstructive sleep apnea (OSA), characterized by repetitive upper airway obstruction, leads to chronic intermittent hypoxia (cIH) and induces cognitive and neuronal network disruptions similar to those observed in Alzheimer's disease (AD). These pathologies are often presented together in the elderly and share some pathophysiological mechanisms.
Pinedo‐Vargas Laura, Méndez‐Salcido Felipe, Lorea‐Hernández Jonathan‐Julio, Victor de Lafuente, Peña‐Ortega Fernando   +4 more
wiley   +1 more source

The Bronchoprotective Effects of Dual Pharmacology, Muscarinic Receptor Antagonist and β₂ Adrenergic Receptor Agonist Navafenterol in Human Small Airways. [PDF]

Cells, 2023
Jude JA, Dainty I, Karmacharya N, Jester W, Panettieri R.   +4 more
europepmc   +1 more source

The effect of McN‐A‐343 on muscarinic receptors in the cerebral cortex and heart [PDF]

, 1983
N.J.M. Birdsall, A. S. V. Burgen, Edward C. Hulme, Jane M. Stockton, Michael J. Zigmond   +4 more
openalex   +1 more source

The Interplay of Cross‐Organ Immune Regulation in Inflammation and Cancer

MedComm, Volume 6, Issue 7, July 2025.
Organs interact dynamically through immune regulation, influencing systemic immune responses and disease progression. We review molecular and cellular mechanisms of cross‐organ immune regulation in inflammation and cancer, focusing on gut, liver, and brain interactions with other organs.
Jie Dou, Jinzuo Jiang, Yangtao Xue, Xiaoqi Jiang, Yongzhuo Jiang, Peng Xiao, Junjie Xu   +6 more
wiley   +1 more source

Role of K+ Channels in M2 Muscarinic Receptor-Mediated Inhibition of Noradrenaline Release From the Rat Stomach

Journal of Pharmacological Sciences, 2004
Previously we reported the cholinergic M2 muscarinic receptor-mediated inhibition of noradrenaline release from the rat stomach (K. Yokotani, Y. Osumi. J Pharmacol Exp Ther. 1993;264:54–60).
Kumiko Nakamura, Shoshiro Okada, Naoko Yamaguchi, Takahiro Shimizu, Keiko Yokotani, Kunihiko Yokotani   +5 more
doaj