Results 161 to 170 of about 56,565 (298)

Muscarinic activity of McN‐A‐343 and its value in muscarinic receptor classification [PDF]

, 1987
Richard M. Eglen, Barry Kenny, A.D. Michel, R.L. Whiting   +3 more
openalex   +1 more source

Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This review highlights the pivotal role of the nervous system in cancer progression, emphasizing how neural–tumor interactions—via synaptic signaling, neurotransmitters, and paracrine factors—reshape the tumor microenvironment. It introduces cancer neuroscience as an emerging field and proposes integrating advanced tools such as AI and optogenetics to ...
Mengyu Yuan, Rongjiao Xi, Yong Kang, Ming‐jie Kuang, Xiaoyuan Ji   +4 more
wiley   +1 more source

Discovering Key Activation Hotspots in the M₂ Muscarinic Receptor. [PDF]

J Am Chem Soc
Sugiura Y, Ikuta T, Sumii Y, Tsujimoto H, Suzuki K, Suno R, Ariff PNABM, Iwata S, Shibata N, Inoue A, Kobayashi T, Kandori H, Katayama K.   +12 more
europepmc   +1 more source

M2 Muscarinic Receptor-Dependent Contractions of Airway Smooth Muscle are Inhibited by Activation of β-Adrenoceptors. [PDF]

Function (Oxf), 2022
Alkawadri T, Wong PY, Fong Z, Lundy FT, McGarvey LP, Hollywood MA, Thornbury KD, Sergeant GP.   +7 more
europepmc   +1 more source

Muscarinic cholinergic-receptor stimulation of specific GTP hydrolysis related to adenylate cyclase activity in canine cardiac sarcolemma. [PDF]

, 1988
J.W. Fleming, Akiko Watanabe
openalex   +1 more source

Modeling presynaptic inhibition by the amyloid precursor protein demonstrates one potential mechanism for preventing runaway synaptic modification in Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Previous simulations of Hebbian associative memory models inspired the malignant synaptic growth hypothesis of Alzheimer's disease (AD), which suggests that cognitive impairments arise due to runaway synaptic modification resulting from poor separation between encoding and retrieval.
Dylan Barber, Michael E. Hasselmo, Heather C. Rice   +2 more
wiley   +1 more source

Developing muscarinic receptor M1 classification models utilizing transfer learning and generative AI techniques. [PDF]

Sci Rep
Dey S, Wallqvist A, AbdulHameed MDM.
europepmc   +1 more source

Differential Actions of Muscarinic Receptor Subtypes in Gastric, Pancreatic, and Colon Cancer. [PDF]

Int J Mol Sci, 2021
Schledwitz A, Sundel MH, Alizadeh M, Hu S, Xie G, Raufman JP.   +5 more
europepmc   +1 more source

Secretory and radioligand binding studies on muscarinic receptors in bovine and feline chromaffin cells.

, 1989
Juan J. Ballesta, Ricardo Borges, Antonio G. Garcı́a, María Jesús Cancelo Hidalgo   +3 more
openalex   +2 more sources

Xerostomia as a Rare Adverse Effect of Low‐Dose Oral Minoxidil: A Case Report With Recurrence After Rechallenge

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Low‐dose oral minoxidil (LDOM) is an emerging option for the treatment of female pattern hair loss (FPHL), generally well tolerated at doses under 1 mg/day. We report a rare adverse event of significant xerostomia in a 74‐year‐old woman with Hashimoto's thyroiditis, receiving 0.5 mg/day of minoxidil for FPHL.
Nicolò Rivetti
wiley   +1 more source