Results 201 to 210 of about 56,565 (298)

The effect of McN‐A‐343 on muscarinic receptors in the cerebral cortex and heart [PDF]

open access: bronze, 1983
N.J.M. Birdsall   +4 more
openalex   +1 more source

Polypharmacy in mice disrupts left ventricular function and structure and promotes proteome reorganisation in an age‐ and sex‐specific fashion

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4625-4646, October 2025.
Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran   +9 more
wiley   +1 more source

Impaired cardiac muscarinic receptor function in dogs with heart failure. [PDF]

open access: bronze, 1988
Dorothy E. Vatner   +6 more
openalex   +1 more source

Exploring the pathophysiology underlying clozapine‐induced enhancement of glutamatergic transmission through L‐glutamate and D‐serine release associated with pannexin1 hemichannels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4710-4728, October 2025.
Abstract Background and purpose Clozapine, an approved antipsychotic for treatment‐resistant schizophrenia (TRS), enhances glutamatergic transmission by increasing exocytosis and non‐exocytosis glutamate release; however, its full action remained to be clarified.
Motohiro Okada   +2 more
wiley   +1 more source

The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions. [PDF]

open access: yesPLoS Biol
Fasciani I   +31 more
europepmc   +1 more source

Muscarinic receptor subtype in the airways

open access: yesJapanese Journal of Pharmacology, 1992
A Onodera   +6 more
openaire   +3 more sources

Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4466-4489, October 2025.
Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota   +4 more
wiley   +1 more source

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