Results 211 to 220 of about 55,054 (301)

Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis. [PDF]

F1000Res
Siafis S, Nomura N, Schneider-Thoma J, Bighelli I, Bannach-Brown A, Ramage FJ, Tinsdeall F, Mantas I, Jauhar S, Natesan S, Vernon AC, de Bartolomeis A, Hölter SM, Drude NI, Tölch U, Hansen WP, Chiocchia V, Howes OD, Priller J, Macleod MR, Salanti G, Leucht S.   +21 more
europepmc   +1 more source

THE EFFECTS OF NORADRENERGIC DENERVATION ON MUSCARINIC RECEPTORS OF SMOOTH MUSCLE [PDF]

, 1982
Thomas M. Bennett, T. Y. Lot, Philip G. Strange   +2 more
openalex   +1 more source

Polypharmacy with tiagabine, levetiracetam, and perampanel in status epilepticus: Insights from EEG, biochemical, and histopathological studies in rats

Epilepsia Open, Volume 10, Issue 3, Page 669-681, June 2025.
Abstract Objective Status epilepticus (SE) is a condition of neurological emergency, which precipitates various functional and morphological changes in the brain. Due to the risk of drug resistance associated with SE, this study aimed to evaluate a multitargeted approach to treat SE by combining clinically used antiseizure drugs. Methods In this study,
Sana Javaid, Faleh Alqahtani, Abida Parveen, Waseem Ashraf, Zohabia Rehman, Syed Muhammad Muneeb Anjum, Tanveer Ahmad, Imran Imran   +7 more
wiley   +1 more source

Muscarinic receptor subtype in the airways

Japanese Journal of Pharmacology, 1992
A Onodera, Mamoru Miura, Kondo S, M. Kagaya, Masaaki Sano, M. Itaba, T. Shioya   +6 more
openaire   +3 more sources

Chemogenetic Control of Striatal Astrocytes Improves Parkinsonian Motor Deficits in Mice

Glia, Volume 73, Issue 6, Page 1188-1202, June 2025.
Main Points Dopamine depletion reduces locomotion‐induced calcium activity in dorsal striatal astrocytes. Chemogenetic activation facilitates astrocyte locomotion responses and improves motor behavior in dopamine lesioned animals. ABSTRACT Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal inputs, which causes ...
Wesley R. Evans, Sindhuja S. Baskar, Angelica Vellore, Ana Raquel Castro E. Costa, Cynthia Jacob, Sanya Ravoori, Abimbola Arigbe, Rafiq Huda   +7 more
wiley   +1 more source

Relationship of the revised anticholinergic drug scale with cultured cell‐based serum anticholinergic activity and cognitive measures in older adults with mild cognitive impairment or remitted depression

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 6, Page 332-340, June 2025.
Abstract Objective The Anticholinergic Drug Scale (ADS) is a commonly used measure of anticholinergic exposure. This study describes an expanded and revised version of the ADS (rADS) and its relationship with cultured cell‐based serum anticholinergic activity (cSAA) and cognitive measures.
Ryan M. Carnahan, Susmita Chandramouleeshwaran, Naba Ahsan, Roger Raymond, Jose N. Nobrega, Wei Wang, Corinne E. Fischer, Alastair J. Flint, Nathan Herrmann, Sanjeev Kumar, Krista L. Lanctôt, Linda Mah, Benoit H. Mulsant, Bruce G. Pollock, Tarek K. Rajji   +14 more
wiley   +1 more source

Muscarinic acetylcholine receptors

Japanese Journal of Pharmacology, 1978
Kunio Takeyasu, Shuji Uchida, Hiroshi Yoshida, Norifumi Yonehara   +3 more
openaire   +2 more sources

Downstream Signaling of Muscarinic M4 Receptors Is Regulated by Receptor Density and Cellular Environment

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Multiple muscarinic M4 receptor modulators are currently advancing in clinical development for the treatment of positive symptoms in schizophrenia, including agonists and positive allosteric modulators. Considering the importance of comprehending M4 receptor pharmacology for these therapeutic applications, this study investigates M4 receptor ...
Madeleine Merz, Charlotte Playle, Monika Palchaudhuri, Oliver Hucke, Ulrike Gross, Daniel Ursu   +5 more
wiley   +1 more source

The Impact of Metformin on Weight and Waist Circumference in Patients Treated With Clozapine: A One‐Year Retrospective Cohort Study

Acta Psychiatrica Scandinavica, Volume 151, Issue 6, Page 719-730, June 2025.
ABSTRACT Background Metformin shows potential in combating clozapine‐induced weight gain (CIWG). However, current evidence for its use remains limited. Through an audit we determined the prevalence of metformin use among clozapine‐treated patients and its impact on weight and waist circumference (WC).
Bee Leng Per, Susan Loeser, Suzanne Edwards, Wen Siew Lee, Lisa R. Wilton, Scott Richard Clark   +5 more
wiley   +1 more source

Secretory and radioligand binding studies on muscarinic receptors in bovine and feline chromaffin cells.

, 1989
Juan J. Ballesta, Ricardo Borges, Antonio G. Garcı́a, María Jesús Cancelo Hidalgo   +3 more
openalex   +2 more sources