Gαq signalling from endosomes: A new conundrum
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley +1 more source
Reactivation-dependent transfer of fear memory between contexts requires M1 muscarinic receptor stimulation in dorsal hippocampus of male rats. [PDF]
Abouelnaga KH+4 more
europepmc +1 more source
The activation of M 3 muscarinic receptor reverses liver injuryvia the Sp1/lncRNA Gm2199/miR-212 axis. [PDF]
Zhang H+9 more
europepmc +1 more source
Postganglionic muscarinic inhibitory receptors in pulmonary parasympathetic nerves in the guinea‐pig [PDF]
David Faulkner+2 more
openalex +1 more source
Microscopy and spectroscopy approaches to study GPCR structure and function
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl+2 more
wiley +1 more source
Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection
Δ9-tetrahydrocannabinol (THC), the chief psychoactive ingredient of cannabis, acts in the brain primarily via cannabinoid CB1 receptors. These receptors are implicated in several forms of synaptic plasticity – depolarization-induced suppression of ...
Michaela Dvorakova+2 more
doaj
Cardiovascular Events with the Use of Long-Acting Muscarinic Receptor Antagonists: An Analysis of the FAERS Database 2020-2023. [PDF]
Matera MG+4 more
europepmc +1 more source
Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease. [PDF]
Scarpa M+14 more
europepmc +1 more source
The muscarinic receptor subtype in mouse pancreatic B‐cells [PDF]
Jean‐Claude Henquin, Myriam Nenquin
openalex +1 more source