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Skeletal Muscle, 2020 Background Distal arthrogryposis (DA) is a group of autosomal dominant skeletal muscle diseases characterized by congenital contractures of distal limb joints.
Yiming Guo +8 more
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Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake.
Comprehensive Physiology, 2020 The skeletal muscle is the largest organ in the body, by mass. It is also the regulator of glucose homeostasis, responsible for 80% of postprandial glucose uptake from the circulation.
Karla E. Merz, D. Thurmond
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Skeletal Muscle Channelopathies [PDF]
Neurotherapeutics, 2018 Skeletal muscle channelopathies are rare heterogeneous diseases with marked genotypic and phenotypic variability. These disorders cause lifetime disability and impact quality of life. Despite advances in understanding of the molecular pathology of these disorders, the diverse phenotypic manifestations remain a challenge in diagnosis, therapeutic ...
Lauren, Phillips, Jaya R, Trivedi
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Skeletal Muscle Mitochondria and Aging: A Review
Journal of Aging Research, 2012 Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines in skeletal muscle mitochondria are thought to play a primary role in this process.
Courtney M. Peterson +2 more
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The Scientific World Journal, 2013 In the beginning of the last century, muscle proteins were viewed as static structural molecules not capable of being utilized by other tissues or organs. This concept was accepted until the 30s, where Rudolf Schoenheimer presented strong evidences about the “Dynamic State of Body Constituents,” which means that skeletal muscle is not only capable of ...
Lucas Guimarães-Ferreira +3 more
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Targeting healthspan to optimally combat non-communicable disease in an aging world
Sports Medicine and Health Science, 2019 Human lifespan and life expectancy have increased worldwide, but the number of years that we spend free of chronic or debilitating disorders, known as healthspan, has not shifted along with increased lifespan.
Joshua C. Drake, Zhen Yan
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The gut microbiota influences skeletal muscle mass and function in mice
Science Translational Medicine, 2019 Transplanting the gut microbiota of pathogen-free mice into germ-free mice improves skeletal muscle mass and strength. Of microbial metabolites and muscle Skeletal muscle is important not only for locomotion but also for regulating metabolic function ...
Shawon Lahiri +18 more
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Single-cell transcriptional profiles in human skeletal muscle
Scientific Reports, 2020 Skeletal muscle is a heterogeneous tissue comprised of muscle fiber and mononuclear cell types that, in addition to movement, influences immunity, metabolism and cognition.
A. Rubenstein +12 more
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Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells [PDF]
Journal of Clinical Investigation, 2010 Skeletal muscle damaged by injury or by degenerative diseases such as muscular dystrophy is able to regenerate new muscle fibers. Regeneration mainly depends upon satellite cells, myogenic progenitors localized between the basal lamina and the muscle fiber membrane.
F. S. Tedesco +4 more
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An updated C. elegans nuclear body muscle transcriptome for studies in muscle formation and function
Skeletal Muscle, 2023 The body muscle is an important tissue used in organisms for proper viability and locomotion. Although this tissue is generally well studied and characterized, and many pathways have been elucidated throughout the years, we still lack a comprehensive ...
Anna L. Schorr +3 more
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