Results 31 to 40 of about 1,532,239 (311)
Targeting healthspan to optimally combat non-communicable disease in an aging world
Sports Medicine and Health Science, 2019 Human lifespan and life expectancy have increased worldwide, but the number of years that we spend free of chronic or debilitating disorders, known as healthspan, has not shifted along with increased lifespan.
Joshua C. Drake, Zhen Yan
doaj +1 more source
Prions in skeletal muscle [PDF]
Proceedings of the National Academy of Sciences, 2002 Considerable evidence argues that consumption of beef products from cattle infected with bovine spongiform encephalopathy (BSE) prions causes new variant Creutzfeldt–Jakob disease. In an effort to prevent new variant Creutzfeldt–Jakob disease, certain “specified offals,” including neural and lymphatic tissues, thought to contain ...
BOSQUE PJ +6 more
openaire +2 more sources
Skeletal muscle ultrasound [PDF]
Neurological Research, 2011 Muscle ultrasound is a convenient technique to visualize normal and pathological muscle tissue as it is non-invasive and real-time. Neuromuscular disorders give rise to structural muscle changes that can be visualized with ultrasound: atrophy can be objectified by measuring muscle thickness, while infiltration of fat and fibrous tissue increases muscle
Pillen, S., Alfen, N. van
openaire +3 more sources
Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor gamma coactivator 1alpha [PDF]
, 2010 Exercise triggers a pleiotropic response in skeletal muscle, which results in a profound remodeling of this tissue. Physical activity-dependent muscle fiber plasticity is regulated by a number of distinct signaling pathways.
Handschin, C. +2 more
core +1 more source
Autophagy in skeletal muscle [PDF]
FEBS Letters, 2010 Muscle mass represents 40–50% of the human body and, in mammals, is one of the most important sites for the control of metabolism. Moreover, during catabolic conditions, muscle proteins are mobilized to sustain gluconeogenesis in the liver and to provide alternative energy substrates for organs.
openaire +3 more sources
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. [PDF]
, 2007 The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) is a key integrator of neuromuscular activity in skeletal muscle.
Handschin, Christoph +15 more
core +1 more source
Skeletal Muscle, 2020 Background In Duchenne muscular dystrophy (DMD), DYSTROPHIN deficiency exposes myofibers to repeated cycles of contraction/degeneration, ultimately leading to muscle loss and replacement by fibrotic tissue.
Luca Caputo +6 more
doaj +1 more source
Changes in intracellular ion activities induced by adrenaline in human and rat skeletal muscle [PDF]
, 1988 To study the stimulating effect of adrenaline (ADR) on active Na+/K+ transport we used double-barrelled ion-sensitive micro-electrodes to measure the activities of extracellular K+ (aKe) and intracellular Na+ (aNai) in isolated preparations of rat soleus
Ballanyi, Klaus, Grafe, Peter
core +1 more source
Skeletal Muscle, 2023 Duchenne muscular dystrophy (DMD) is caused by the lack of dystrophin, a cytoskeletal protein essential for the preservation of the structural integrity of the muscle cell membrane.
Dongwoo Hahn +6 more
doaj +1 more source
The regulation of metabolic gene expression in human skeletal muscle by exercise: the influence of exercise intensity and contraction frequency [PDF]
, 2010 Skeletal muscle contraction increases energy expenditure and improves metabolic flexibility, but is also a key regulator of metabolic gene expression.
Carson, Brian
core +2 more sources