Results 21 to 30 of about 362,047 (272)

Modelling and Analysis of Magnetic Fields from Skeletal Muscle for Valuable Physiological Measurements [PDF]

open access: yesarXiv, 2021
MagnetoMyoGraphy (MMG) is a method of studying muscle function via weak magnetic fields generated from human active organs and tissues. The correspondence between MMG and electromyography means directly derived from the Maxwell-Amp\`ere law. Here, upon briefly describing the principles of voltage distribution inside skeletal muscles due to the ...
arxiv  

Myoblast fusion confusion: the resolution begins

open access: yesSkeletal Muscle, 2018
The fusion of muscle precursor cells is a required event for proper skeletal muscle development and regeneration. Numerous proteins have been implicated to function in myoblast fusion; however, the majority are expressed in diverse tissues and regulate ...
Srihari C. Sampath   +2 more
doaj   +1 more source

Accelerated, physics-inspired inference of skeletal muscle microstructure from diffusion-weighted MRI [PDF]

open access: yesarXiv, 2023
Muscle health is a critical component of overall health and quality of life. However, current measures of skeletal muscle health take limited account of microstructural variations within muscle, which play a crucial role in mediating muscle function. To address this, we present a physics-inspired, machine learning-based framework for the non-invasive ...
arxiv  

MyoD-dependent regulation of NF-κB activity couples cell-cycle withdrawal to myogenic differentiation

open access: yesSkeletal Muscle, 2012
Background Mice lacking MyoD exhibit delayed skeletal muscle regeneration and markedly enhanced numbers of satellite cells. Myoblasts isolated from MyoD-/- myoblasts proliferate more rapidly than wild type myoblasts, display a dramatic delay in ...
Parker Maura H   +6 more
doaj   +1 more source

The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis

open access: yesSkeletal Muscle, 2018
Background Members of the ZFP36 family of RNA-binding proteins regulate gene expression post-transcriptionally by binding to AU-rich elements in the 3’UTR of mRNA and stimulating mRNA degradation.
Hema Bye-A-Jee   +6 more
doaj   +1 more source

Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model

open access: yesSkeletal Muscle, 2020
Background Pulmonary hypertension leads to right ventricular heart failure and ultimately to cardiac cachexia. Cardiac cachexia induces skeletal muscles atrophy and contractile dysfunction.
Thanh Nguyen   +7 more
doaj   +1 more source

Unexpected evolutionarily conserved rapid effects of viral infection on oxytocin receptor and TGF-β/pSmad3

open access: yesSkeletal Muscle, 2017
Background shRNA lentiviral vectors are extensively used for gene knockdowns in mammalian cells, and non-target shRNAs typically are considered the proper experimental control for general changes caused by RNAi.
Yutong Liu, Irina Conboy
doaj   +1 more source

mTORC2 affects the maintenance of the muscle stem cell pool

open access: yesSkeletal Muscle, 2019
Background The mammalian target of rapamycin complex 2 (mTORC2), containing the essential protein rictor, regulates cellular metabolism and cytoskeletal organization by phosphorylating protein kinases, such as PKB/Akt, PKC, and SGK.
Nathalie Rion   +5 more
doaj   +1 more source

Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models

open access: yesSkeletal Muscle, 2011
A highly conserved signaling pathway involving insulin-like growth factor 1 (IGF1), and a cascade of intracellular components that mediate its effects, plays a major role in the regulation of skeletal muscle growth. A central component in this cascade is
Schiaffino Stefano, Mammucari Cristina
doaj   +1 more source

SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes

open access: yesSkeletal Muscle, 2017
Background Facioscapulohumeral muscular dystrophy (FSHD) is in most cases caused by a contraction of the D4Z4 macrosatellite repeat on chromosome 4 (FSHD1) or by mutations in the SMCHD1 or DNMT3B gene (FSHD2).
Amanda G. Mason   +12 more
doaj   +1 more source

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