Results 21 to 30 of about 362,047 (272)
Modelling and Analysis of Magnetic Fields from Skeletal Muscle for Valuable Physiological Measurements [PDF]
MagnetoMyoGraphy (MMG) is a method of studying muscle function via weak magnetic fields generated from human active organs and tissues. The correspondence between MMG and electromyography means directly derived from the Maxwell-Amp\`ere law. Here, upon briefly describing the principles of voltage distribution inside skeletal muscles due to the ...
arxiv
Myoblast fusion confusion: the resolution begins
The fusion of muscle precursor cells is a required event for proper skeletal muscle development and regeneration. Numerous proteins have been implicated to function in myoblast fusion; however, the majority are expressed in diverse tissues and regulate ...
Srihari C. Sampath+2 more
doaj +1 more source
Accelerated, physics-inspired inference of skeletal muscle microstructure from diffusion-weighted MRI [PDF]
Muscle health is a critical component of overall health and quality of life. However, current measures of skeletal muscle health take limited account of microstructural variations within muscle, which play a crucial role in mediating muscle function. To address this, we present a physics-inspired, machine learning-based framework for the non-invasive ...
arxiv
Background Mice lacking MyoD exhibit delayed skeletal muscle regeneration and markedly enhanced numbers of satellite cells. Myoblasts isolated from MyoD-/- myoblasts proliferate more rapidly than wild type myoblasts, display a dramatic delay in ...
Parker Maura H+6 more
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The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis
Background Members of the ZFP36 family of RNA-binding proteins regulate gene expression post-transcriptionally by binding to AU-rich elements in the 3’UTR of mRNA and stimulating mRNA degradation.
Hema Bye-A-Jee+6 more
doaj +1 more source
Background Pulmonary hypertension leads to right ventricular heart failure and ultimately to cardiac cachexia. Cardiac cachexia induces skeletal muscles atrophy and contractile dysfunction.
Thanh Nguyen+7 more
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Background shRNA lentiviral vectors are extensively used for gene knockdowns in mammalian cells, and non-target shRNAs typically are considered the proper experimental control for general changes caused by RNAi.
Yutong Liu, Irina Conboy
doaj +1 more source
mTORC2 affects the maintenance of the muscle stem cell pool
Background The mammalian target of rapamycin complex 2 (mTORC2), containing the essential protein rictor, regulates cellular metabolism and cytoskeletal organization by phosphorylating protein kinases, such as PKB/Akt, PKC, and SGK.
Nathalie Rion+5 more
doaj +1 more source
Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models
A highly conserved signaling pathway involving insulin-like growth factor 1 (IGF1), and a cascade of intracellular components that mediate its effects, plays a major role in the regulation of skeletal muscle growth. A central component in this cascade is
Schiaffino Stefano, Mammucari Cristina
doaj +1 more source
SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes
Background Facioscapulohumeral muscular dystrophy (FSHD) is in most cases caused by a contraction of the D4Z4 macrosatellite repeat on chromosome 4 (FSHD1) or by mutations in the SMCHD1 or DNMT3B gene (FSHD2).
Amanda G. Mason+12 more
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