Results 1 to 10 of about 435,139 (141)

Ca2+‐activated Cl− channels (TMEM16A) underlie spontaneous electrical activity in isolated mouse corpus cavernosum smooth muscle cells

open access: yesPhysiological Reports, 2022
Penile detumescence is maintained by tonic contraction of corpus cavernosum smooth muscle cells (CCSMC), but the underlying mechanisms have not been fully elucidated.
Xin Rui Lim   +4 more
doaj   +1 more source

Arterial Smooth Muscle [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2014
The prime function of the arterial smooth muscle cell (SMC) in adult individuals is to contract and relax, thereby regulating blood flow to target tissues. However, in several vascular diseases, arterial SMCs in the adult vessel undergo major changes in structure and function.
Valerie Z, Wall, Karin E, Bornfeldt
openaire   +2 more sources

Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice

open access: yesScientific Reports, 2022
Inhibition of Notch signaling in macrophages is known to reduce inflammation, however, its role in regulating vascular hyporeactivity in sepsis is unknown. Thus we aimed to evaluate the effect of sepsis on vascular Notch signaling.
Vandana Singh   +8 more
doaj   +1 more source

Role of smooth muscle progenitor cells in vascular mechanical injury and repair

open access: yesMedicine in Novel Technology and Devices, 2022
Smooth muscle progenitor cells are precursor cells that express both smooth muscle cell and stem cell markers, and can differentiate into smooth muscle cells under specific condition.
Zhu-feng Dong   +7 more
doaj   +1 more source

Characterization of Cecal Smooth Muscle Contraction in Laying Hens

open access: yesVeterinary Sciences, 2021
The ceca play an important role in the physiology of the gastrointestinal tract in chickens. Nevertheless, there is a gap of knowledge regarding the functionality of the ceca in poultry, especially with respect to physiological cecal smooth muscle ...
Katrin Röhm   +3 more
doaj   +1 more source

Smooth muscle strips for intestinal tissue engineering. [PDF]

open access: yesPLoS ONE, 2014
Functionally contracting smooth muscle is an essential part of the engineered intestine that has not been replicated in vitro. The purpose of this study is to produce contracting smooth muscle in culture by maintaining the native smooth muscle ...
Christopher M Walthers   +3 more
doaj   +1 more source

Defining smooth muscle cells and smooth muscle injury [PDF]

open access: yesJournal of Clinical Investigation, 2005
For 3 decades, terms such as synthetic phenotype and contractile phenotype have been used to imply the existence of a specific mechanism for smooth muscle cell (SMC) responses to injury. In this issue of the JCI, Hendrix et al. offer a far more precise approach to examining the mechanisms of SMC responses to injury, focused not on general changes in ...
William M, Mahoney, Stephen M, Schwartz
openaire   +2 more sources

Comparison of pain intensity, smooth muscle cells density, and alpha-smooth muscle actin expression in ovarial and peritoneal endometriosis

open access: yesMajalah Obstetri dan Ginekologi, 2021
HIGHLIGHT 1. Pain intensity, smooth muscle cells density, and alpha-SMA expression can be used to analyze the role of smooth muscle in endometriosis. 2.
Sutrisno Sutrisno   +2 more
doaj   +1 more source

Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction

open access: yesFrontiers in Physiology, 2020
Both smooth muscle (SM) and non-muscle (NM) myosin II are expressed in hollow organs such as the bladder and uterus, but their respective roles in contraction and corresponding physiological functions remain to be determined.
Jie Sun   +13 more
doaj   +1 more source

Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]

open access: yesPLoS ONE, 2014
Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy