Results 281 to 290 of about 490,082 (308)
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Actions of Nicorandil on Vascular Smooth Muscles
Journal of Cardiovascular Pharmacology, 1987The action of nicorandil on vascular smooth muscles has been studied in vitro using the microelectrode, Ca-transient, isometric tension recording methods, and the bioassay methods of cyclic nucleotides and inositol phospholipids. Nicorandil increased Ca-insensitive K conductance and hyperpolarized the membrane and thus prevented the activation of the ...
Hirosi Kuriyama +6 more
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Vascular Smooth Muscle Calcium Channels
Journal of Cardiovascular Pharmacology, 1987Vascular smooth muscle Ca channels function in excitation-contraction coupling. A survey of recent literature reveals several types of excitable Ca channels. There are at least two plasmalemmal Ca channels that are primarily activated by depolarization. In addition, there also exists evidence for the presence of Ca channels in conduit arteries that are
H. Yamamoto +3 more
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Chemokine Receptors in Vascular Smooth Muscle
Microcirculation, 2003ABSTRACTAtherosclerosis is considered to be an inflammatory disease. Chemokines are low‐molecular‐weight proteins that exert their effects, in part, through mediating leukocytic infiltration into the vessel wall. Recently, studies have determined that chemokines and their receptors are present, and function on other cellular components comprising the ...
Mark B. Taubman +2 more
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1996
Smooth Muscle Tissue. The visceral mesenchyma (splanchnopleura) is the principal source for smooth muscle tissue. It also forms the layer-shaped muscle and connective tissue strata of the vessel walls. The vascular system of the human embryo develops from blood islets in the middle of the third week, shortly before somite formation, when the embryo can
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Smooth Muscle Tissue. The visceral mesenchyma (splanchnopleura) is the principal source for smooth muscle tissue. It also forms the layer-shaped muscle and connective tissue strata of the vessel walls. The vascular system of the human embryo develops from blood islets in the middle of the third week, shortly before somite formation, when the embryo can
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Calcium Kinetics in Vascular Smooth Muscle
Chest, 1985The accumulation, binding, and mobilization of Ca++ in vascular smooth muscle directly affects intracellular free Ca++ levels and contractility. Techniques have been developed to delineate Ca++ uptake and efflux parameters in isolated vessels. Similar Ca++-related components are present in different types of vessels, but their relative importance for ...
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Vascular smooth muscle and arterial calcification
Zeitschrift f�r Kardiologie, 2000Smooth muscle cultures can calcify under certain circumstances. As a model system these cultures therefore provide information on why calcification occurs in atherosclerotic plaques. Whether all smooth muscle cells (under certain conditions), or only specific populations, can produce this mineralization has not been resolved.
Campbell, G. R., Campbell, J. H.
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Sarcoglycans in Vascular Smooth and Striated Muscle
Trends in Cardiovascular Medicine, 2003Sarcoglycans are transmembrane proteins important in the maintenance of proper muscle function. Together, the sarcoglycans form a heteromeric complex that interacts with dystrophin, dystroglycan, and filamin C to form a mechanosignaling complex. Mutations in the genes encoding sarcoglycan can produce cardiomyopathy and muscular dystrophy.
Elizabeth M. McNally, Matthew T. Wheeler
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Vascular smooth muscle and exercise
Sports Medicine, Training and Rehabilitation, 1998Vascular smooth muscle is under the influence of local (metabolic, autoregulatory and endothelial), reflex (autonomic nervous system), and hormonal (norepinephrine, epinephrine, angioten‐sin, and vasopressin) regulatory mechanisms. These regulatory mechanisms interact during exercise in a coordinated manner to assure adequate tissue blood flow while ...
Stephen E. DiCarlo +3 more
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Ultrastructure of Vascular Smooth Muscle
2017Vascular smooth muscle, which is located in the tunica media layer of the vascular wall, is the primary player to enable the blood vessel to constrict and dilate. This is fulfilled by the interaction of thin and thick filaments of the contractile apparatus. These filaments in the smooth muscle are organized differently from striated muscle, termed side
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Metabolism of Vascular Smooth Muscle
2017Metabolism refers to chemical reactions that occur in living organisms necessary to maintain its structure and activities, to respond to environment changes, and to grow and reproduce. In this chapter we focus on the metabolism related to energy supply for the contractility of vascular smooth muscle (VSM), including the characteristics of energy ...
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