Results 271 to 280 of about 297,987 (316)
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Vascular Smooth Muscle Energetics
Journal of Cardiovascular Pharmacology, 1984ATP utilization (delta approximately P) during an isometric contraction has been studied in terms of both measurements of oxygen consumption and lactate production as well as of the tissue nucleotide and metabolite levels. The contribution of breakdown of preformed ATP and phosphocreatine (PCr) pools to delta approximately P during contraction is minor
R J, Paul, J M, Krisanda, R M, Lynch
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Leptin and Vascular Smooth Muscle
Current Vascular Pharmacology, 2006Leptin has received extensive attention as an endogenously produced satiety factor. Although once considered to be solely derived from adipose tissue, it is now apparent that leptin can be produced by various tissues including those comprising the cardiovascular system such as blood vessels and cardiomyocytes. Moreover, leptin receptors (OBR) have been
Asad, Zeidan, Morris, Karmazyn
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The Vascular Smooth Muscle Cell In Culture
Thrombosis and Haemostasis, 1981When smooth muscle from the aortic media of adult pigs, monkeys and rabbits are dispersed into single cells and seeded into primary culture they are in the contractile phenotype and do not undergo cell division when challenged with 5 or 10% whole blood serum.
Campbell, GR, Chamleycampbell, JH
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Mechanotransduction by Vascular Smooth Muscle
Journal of Vascular Research, 2008Mechanotransduction by vascular smooth muscle (VSM) is defined as a cellular response (contraction, secretion, growth, division) to transmural pressure or stretch. This review includes an overview of the physical forces VSM cells experience in vivo, consideration of experimental techiques used to study VSM mechanotransduction, and a discussion of the ...
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Mechanics of Vascular Smooth Muscle
Comprehensive Physiology, 2016ABSTRACT Vascular smooth muscle (VSM; see Table 1 for a list of abbreviations) is a heterogeneous biomaterial comprised of cells and extracellular matrix. By surrounding tubes of endothelial cells, VSM forms a regulated network, the vasculature, through which oxygenated blood supplies specialized organs ...
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Effect of angiotensin on vascular smooth muscles
Pfl�gers Archiv European Journal of Physiology, 1969The response of vascular smooth muscle to angiotensin has been studied on helical strips of canine coronary, renal, and carotid arteries and on strips of the thoracic aorta from guinea pigs and rats.
P, Walter, E, Bassenge
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Calcium Kinetics in Vascular Smooth Muscle
Chest, 1985The accumulation, binding, and mobilization of Ca++ in vascular smooth muscle directly affects intracellular free Ca++ levels and contractility. Techniques have been developed to delineate Ca++ uptake and efflux parameters in isolated vessels. Similar Ca++-related components are present in different types of vessels, but their relative importance for ...
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2005
Vascular smooth muscle cells (VSMCs) are a major component of arteries, veins and small blood vessels. Their main function is to maintain vascular tone, via co-ordinated vasoconstriction and vasorelaxation, thereby regulating blood pressure and flow.
Diane Proudfoot, Catherine M Shanahan
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Vascular smooth muscle cells (VSMCs) are a major component of arteries, veins and small blood vessels. Their main function is to maintain vascular tone, via co-ordinated vasoconstriction and vasorelaxation, thereby regulating blood pressure and flow.
Diane Proudfoot, Catherine M Shanahan
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Oxygen sensors in vascular smooth muscle
Journal of Applied Physiology, 1994Inhibition or activation of cellular function due to acute decreases in PO2 can be considered in terms of two different processes: 1) a sensor that monitors PO2 decreases and 2) transduction systems directed from the O2 sensor to reactions that control cellular function.
Y, Katayama +3 more
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Intracellular Signaling in Vascular Smooth Muscle
1993The two major modalities of pharmacomechanical coupling, inositol 1,4,5, trisphosphate induced Ca2+ release and modulation of Ca(2+)-sensitivity, are reviewed. Recent studies show that although changes in cytoplasmic Ca2+ play the major role in regulating smooth muscle contraction, agonists can also significantly affect the contractile state by ...
A V, Somlyo, A P, Somlyo
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